Actively Recruiting

Age: 17Years - 45Years
FEMALE
NCT05647109

Patient-derived Tumor-like Cell Clusters Predict Progesterone Sensitivity in Patients With Early Endometrial Cancer

Led by Peking University People's Hospital · Updated on 2025-05-04

244

Participants Needed

1

Research Sites

217 weeks

Total Duration

On this page

Sponsors

P

Peking University People's Hospital

Lead Sponsor

P

Peking University

Collaborating Sponsor

AI-Summary

What this Trial Is About

To construct a prediction model of progesterone sensitivity in patients with endometrial cancer treated with fertility preservation

CONDITIONS

Official Title

Patient-derived Tumor-like Cell Clusters Predict Progesterone Sensitivity in Patients With Early Endometrial Cancer

Who Can Participate

Age: 17Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis by hysteroscopy of atypical endometrial hyperplasia or well-differentiated early endometrial carcinoma grade 1 without myometrial invasion
  • No signs of suspected extrauterine involvement on enhanced MRI, CT, or ultrasound
  • Desire to preserve reproductive function or uterus
  • Good compliance with treatment and follow-up
Not Eligible

You will not qualify if you...

  • Acute liver disease, liver tumor, or kidney dysfunction
  • Pregnancy or potential pregnancy
  • Diagnosis of any cancer in the reproductive system
  • Acute severe disease such as stroke, heart attack, or history of thrombosis
  • Allergy or contraindication to Medroxyprogesterone acetate (MPA) or Megestrol acetate (MA)
  • Other reproductive dysfunction factors
  • Strong desire for uterine removal or alternative conservative treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University People's Hospital

Beijing, Beijing Municipality, China

Actively Recruiting

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Research Team

W

WANG JIANLIU, PhD/MD

CONTACT

H

HE YIJIAO, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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