Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT05546099

Patient-driven Management of BP in CKD

Led by VA Office of Research and Development · Updated on 2025-10-30

160

Participants Needed

1

Research Sites

205 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The proposed research will evaluate if patients managing their blood pressure medications under the guidance of a clinical pharmacist works better to lower blood pressure than patients monitoring their blood pressure at home and the standard care. 60 Veterans with chronic kidney disease (CKD) will be included in the study. The study will further evaluate factors that may influence the Veteran to accept the self-management approach and what factors in the VHA healthcare system affect the implementation of the self-management approach.

CONDITIONS

Official Title

Patient-driven Management of BP in CKD

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age �318 years
  • Diagnosis of stage 3 or 4 chronic kidney disease (estimated GFR 15-59 mL/min/1.73m2)
  • Or stage 2 chronic kidney disease (estimated GFR 60-89 mL/min/1.73m2) with elevated urinary albumin/creatinine ratio (300 mg/g if no diabetes or 30 mg/g if diabetes)
  • Uncontrolled hypertension with an average of two systolic blood pressure readings above 140 mmHg
Not Eligible

You will not qualify if you...

  • Severely uncontrolled hypertension with systolic blood pressure above 180 mmHg
  • Resistant hypertension requiring four blood pressure medications
  • Orthostatic hypotension defined as a drop in systolic BP by 20 mmHg or diastolic BP by 10 mmHg after standing for 3 minutes
  • Severe chronic kidney disease with estimated GFR below 20 mL/min/1.73m2
  • Life expectancy less than 1 year
  • Severe liver disease
  • Severe congestive heart failure
  • Severe cognitive decline due to dementia
  • Pregnancy, breastfeeding, or unwillingness to use adequate birth control

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Iowa City VA Health Care System, Iowa City, IA

Iowa City, Iowa, United States, 52246-2292

Actively Recruiting

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Research Team

D

Diana Jalal, MD

CONTACT

K

Katharine M Geasland, RN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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