Actively Recruiting

Age: 18Years +
All Genders
NCT07105631

Patient-reported Outcomes (PRO) and Treatment Outcomes of Chinese Patients With MSS-type Advanced Colorectal Cancer Who Received the Zidovudine Combination Regimen in the Real World

Led by West China Hospital · Updated on 2025-08-06

300

Participants Needed

1

Research Sites

107 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Chidamide + sintilimab ± bevacizumab regimen has become a post-treatment option for clinicians and patients after being included in the guidelines. The CAPability-01 study is a phase II RCT, with a limited number of enrolled subjects. Further observation of the safety and clinical real-world application status of the sidibemab combination regimen is needed in a larger sample size prospective observational cohort study. The primary endpoint of this study is the safety events of the sidibemab combination regimen.

CONDITIONS

Official Title

Patient-reported Outcomes (PRO) and Treatment Outcomes of Chinese Patients With MSS-type Advanced Colorectal Cancer Who Received the Zidovudine Combination Regimen in the Real World

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Advanced colorectal cancer confirmed by tissue testing
  • Cancer confirmed as MSS or pMMR type by immunohistochemistry or genetic testing
  • Investigator deems cediranib combined with immune checkpoint inhibitors treatment suitable
  • Clear consciousness and ability to answer questions correctly
  • Ability to use mobile phones with internet access (3G/4G/5G)
Not Eligible

You will not qualify if you...

  • Serious complications interfering with safety and efficacy analysis
  • Investigator determines subject is unsuitable for study participation

AI-Screening

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Trial Site Locations

Total: 1 location

1

West China Hospital Sichuan University

Chengdu, Sichuan, China, 827153

Actively Recruiting

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Research Team

M

meng Qiu PhD West China Hospital of Sichuan university

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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