Actively Recruiting
Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared
Led by Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Updated on 2026-04-23
90
Participants Needed
1
Research Sites
127 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study aims to assess the direct patient-reported perception (PROs) of individuals affected by IDH-mutant, grade 2 gliomas undergoing radiotherapy or pharmacological treatment with vorasidenib. To evaluate quality of life, perception of treatment-related symptoms, and anxiety levels during therapy by comparing patients receiving radiotherapy with those receiving pharmacological treatment with vorasidenib. The control group will consist of patients with IDH-mutant, grade 2 gliomas who are under clinical and radiological follow-up only. To assess the feasibility of using PROMs in routine clinical practice. To analyze patient-reported critical issues in order to qualitatively improve care pathways.
CONDITIONS
Official Title
Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Histological diagnosis of IDH mutant, grade 2 glioma
- Consent to treatment
- Consent to the administration of PROM questionnaires
You will not qualify if you...
- Cognitive impairment or mental disability
- Dementia or severe cognitive disorders preventing understanding of questionnaires
- Uncontrolled severe psychiatric disorders such as schizophrenia or untreated psychosis
- Language barriers or inability to understand the questionnaire language
- Literacy issues preventing reading or writing
- Non-adherence or poor cooperation
- Refusal to complete the questionnaires
- Conditions that may influence questionnaire outcomes
- Use of medications that impair cognitive abilities such as sedatives or antipsychotics
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Istituto Neurologico Carlo Besta
Milan, Italy
Actively Recruiting
Research Team
C
Cristiana Pedone, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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