Actively Recruiting

Age: 18Years +
All Genders
ID05339568

A Multicenter, Randomized Study Evaluating Long-term Benefits of Patient-wide Management Platform in Locally Advanced or Metastatic Non-small Cell Lung Cancer

Led by Qianfoshan Hospital · Updated on 2022-09-08

1268

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are exploring whether using a patient process management platform for managing and following up with patients who have locally advanced or metastatic non-small cell lung cancer (NSCLC) can help extend survival and improve quality of life. NSCLC treatment varies and includes radiation, chemotherapy, targeted therapy, and immunotherapy, but the disease often leads to complications and mental health challenges like anxiety and insomnia. Effective follow-up and management are crucial to addressing these issues and supporting patients through their treatment journey. The study compares two groups: one managed through a whole process follow-up platform where patients can report symptoms, receive reminders for hospital visits and medication, and access educational materials; the other group receives routine follow-up care from investigators or nurses at the hospital. The platform aims to improve treatment adherence, reduce complications, and support psychological well-being. The study is open, randomized, and parallel, conducted across multiple centers. Participants will be monitored up to 96 months for overall survival, progression-free survival, adverse events, follow-up compliance, quality of life, and follow-up satisfaction. Data collection includes patient-reported symptoms and educational engagement via the platform or standard hospital follow-up. Researchers will assess the long-term benefits of this management approach on patient outcomes and experience. The study started in May 2022 and continues until August 2030, with no upper age limit for participants.

CONDITIONS

Brief Title

Patient's Whole Process Follow-up Management(HOPE-1)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Fully understand the research and voluntarily sign the informed consent form
  • Male or female aged 18 years or older at the time of consent
  • Diagnosed pathologically or cytologically with non-small cell lung cancer (NSCLC)
  • Classified as stage IIB, III, or IV NSCLC according to the 8th edition AJCC
  • Not suitable for radical treatment or refuse surgery
  • Life expectancy of at least 3 months
  • Able to use a smartphone
Not Eligible

You will not qualify if you...

  • Patients with mental illness
  • Presence of any other malignant tumor
  • Patients expected to undergo radical surgery
  • Currently participating in other clinical trials
  • Judged by the investigator as unsuitable to participate in the trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 96 months

Participants are observed and followed up over time to collect information on survival, quality of life, adverse events, and compliance with follow-up procedures.

Regular visits depending on cohort assignment and follow-up needs

Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Shandong First Medical University

Jinan, Shandong, China

Actively Recruiting

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Research Team

J

Jiandong ZHANG

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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