Actively Recruiting
Patients With and Without Phonotrauma
Led by University of Texas Southwestern Medical Center · Updated on 2025-07-30
100
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
There is a substantial need to identify objective measures associated with hyperadduction of the vocal folds to recognize those at higher risk of developing phonotrauma so that risk mitigation strategies can be implemented before phonotrauma develops. The overall objective of this proposed project is to investigate the sensitivity and direction of change in cepstral peak prominence (CPP) and the magnitude difference between the first two harmonics of the voice spectrum (H1-H2) in response to varied phonation patterns, which will be addressed using the following two aims: Aim 1: Determine how CPP and H1-H2 change as a function of using pressed voice production in individuals without laryngeal pathology. Aim 2: Examine the sensitivity (minimally detectable change) and responsiveness (minimal clinically important difference) of CPP and H1-H2 to detect changes in different voice production conditions.
CONDITIONS
Official Title
Patients With and Without Phonotrauma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- For control group: no history or current voice disorder
- For control group: voice presentation within functional limits as determined by a voice specialist
- For patient group: diagnosed with phonotrauma by a laryngologist (including vocal fold nodules, polyps, pseudocysts, or mid-fold edema)
You will not qualify if you...
- Atypical auditory-perceptual voice presentation
- History of voice disorder or laryngeal surgery (control group)
- Voice disorders unrelated to phonotrauma (patient group, e.g., vocal fold immobility, laryngeal dystonia, primary muscle tension dysphonia)
- Previous voice therapy or laryngeal surgery (patient group)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UT Southwestern Medical Center
Dallas, Texas, United States, 75235
Actively Recruiting
Research Team
L
Laura Toles, PhD
CONTACT
P
Paula Arellano-Cruz
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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