Changes in Eye Surface and Cornea After Cataract Surgery and Their Link to Inflammation and Pain Biomarkers

What this Trial Is About

Researchers are exploring patterns of dry eye disease DED after cataract surgery, focusing on changes to the eye surface and cornea, patients personal assessment of symptoms, and links with eye inflammation and pain markers. This observational study involves adults aged 50 to 90 who have undergone uncomplicated cataract surgery performed by the same experienced surgeon, aiming to understand the long-term effects on ocular health. Participants are divided into two groups one will use artificial tears sodium hyaluronate 0.2% starting 7 days before surgery and continuing for 3 months after the procedure, applied four times daily. The other group will not use any artificial tears before or after surgery. The study tracks these groups over time to compare outcomes related to eye surface lubrication and healing. Throughout the study, participants undergo multiple assessments before surgery and at 1 week, 1 month, 3 months, 6 months, and 12 months after surgery. These include evaluations of eye surface changes, corneal structure, tear composition including inflammatory markers, eye sensitivity, and visual function tests. Questionnaires about dry eye symptoms and quality of vision are also completed. The study monitors these measures to understand how cataract surgery and tear treatment affect eye health over a year.

The Pattern of Dry Eye Disease After Cataract Surgery