Actively Recruiting
pBFS-guided Multi-target cTBS for Aphasia After Stroke
Led by Changping Laboratory · Updated on 2025-04-04
60
Participants Needed
3
Research Sites
110 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, a randomized, double-blind, parallel-controlled trial was employed to evaluate the effectiveness and safety of personalized brain functional sectors (pBFS) technology-guided continuous theta burst stimulation (cTBS) on the inferior frontal gyrus (IFG) combined with the superior temporal gyrus (STG) and the superior frontal gyrus (SFG) for language function recovery in post-stroke aphasic patients.
CONDITIONS
Official Title
pBFS-guided Multi-target cTBS for Aphasia After Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 35 and 75 years old (inclusive)
- Diagnosis of ischemic or hemorrhagic stroke with lesions in the left hemisphere, illness duration from 15 days to 6 months
- Diagnosed with aphasia using the Chinese version of Western Aphasia Battery with a score less than 93.8
- First stroke occurrence
- Normal language function before stroke and native Chinese speaker with at least 6 years of education
- Able to understand the trial and provide signed informed consent
You will not qualify if you...
- Combined dysarthria with NIHSS item 10 score of 2 or higher
- Aphasia caused by bilateral hemisphere stroke, brain tumor, traumatic brain injury, Parkinson's disease, motor neuron disease, or other diseases
- Implanted electronic devices such as pacemakers or cochlear implants, or MRI or TMS contraindications
- History of epilepsy
- Severe uncontrolled systemic diseases affecting heart, lungs, liver, kidneys
- Consciousness disorders with NIHSS 1(a) score of 1 or higher
- Malignant hypertension
- Severe organic diseases like malignant tumors with life expectancy under 1 year
- Severe hearing, visual, cognitive impairment or inability to cooperate
- Severe depression, anxiety, or other mental illnesses preventing trial completion
- Received other neuromodulation treatments within 3 months prior
- History of alcoholism, drug abuse, or substance abuse
- Other abnormalities judged unsuitable by researchers
- Unable to complete follow-up due to geographic or other reasons
- Women who are pregnant, breastfeeding, or planning pregnancy during the trial
- Currently participating in other clinical trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Affiliated Hospital of Hebei University
Baoding, Hebei, China
Actively Recruiting
2
Affiliated Hospital of Chengde Medical University
Chengde, Hebei, China
Actively Recruiting
3
Hebei General Hospital
Shijiazhuang, Hebei, China
Actively Recruiting
Research Team
J
Jianting Huang, MD,PhD
CONTACT
R
Ruiqi Pan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here