Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
NCT06325956

PCOS Immune Function Predicts Metformin Efficacy

Led by Shanghai 10th People's Hospital · Updated on 2024-03-22

100

Participants Needed

1

Research Sites

119 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study, the investigators will include PCOS patients who meet the trial criteria, introduce participants to the content of this study, and invite participants to participate. The immune function of peripheral blood samples of PCOS patients was detected by flow cytometry. Participants were further treated with metformin for 6 months and followed up after the intervention. The objective of this study was to investigate immune markers related to the efficacy of metformin in PCOS patients and to predict the efficacy of metformin in PCOS patients using immune function.

CONDITIONS

Official Title

PCOS Immune Function Predicts Metformin Efficacy

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 to 45 years
  • Diagnosis of Polycystic Ovary Syndrome (PCOS) using the Rotterdam diagnosis criteria (2003)
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Hyperthyroidism or hypothyroidism
  • Severe liver and kidney function injury
  • Cancer patients
  • Severe infection, severe anemia, neutropenia, or other blood system diseases
  • Type 1 diabetes, single-gene mutated diabetes, or other secondary diabetes
  • Patients with mental illness or intellectual disability
  • Use of drugs for PCOS treatment in the last three months
  • Long history of hormone therapy
  • Currently or recently participating in another clinical trial

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Department of Endocrinology, Shanghai Tenth People's Hospital

Shanghai, China, 200072

Actively Recruiting

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Research Team

M

Manna Zhang, doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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