Actively Recruiting
PD-L1 Specific [68Ga]Ga-THP-PDL1-3 Probe for PET Imaging in Solid Tumors
Led by Hua Zhu · Updated on 2026-04-07
50
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To utilize the \[68Ga\]Ga-THP-PDL1-3 molecular probe to non-invasively detect PD-L1 expression in primary and metastatic lesions of patients with solid tumors. Furthermore, to assess the heterogeneity of PD-L1 expression within the same lesion and across different lesions, and to observe changes in PD-L1 expression during the course of treatment. This approach aims to facilitate patient screening, therapeutic monitoring, and early warning of drug resistance and/or recurrence or metastasis in the treatment of solid tumors with high PD-L1 expression, ultimately enabling personalized targeted therapy in oncology.
CONDITIONS
Official Title
PD-L1 Specific [68Ga]Ga-THP-PDL1-3 Probe for PET Imaging in Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-70 years with an ECOG performance status of 0 or 1
- Diagnosis of solid tumors
- Presence of measurable lesions on imaging exams
- Expected survival of at least 12 weeks
You will not qualify if you...
- Severe liver or kidney dysfunction
- Women who are pregnant, breastfeeding, or planning pregnancy
- Unable to lie flat on the back for 30 minutes
- Refusal to participate in the study
- Diagnosis of claustrophobia or other psychiatric disorders
- Any other condition the investigator considers unsuitable for participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Cancer Hospital
Beijing, Beijing Municipality, China, 100142
Actively Recruiting
Research Team
H
Hua Zhu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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