Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06696742

PD1 Inhibitors Combined With Clostridium Butyricum for Urothelial Carcinoma

Led by The First Affiliated Hospital with Nanjing Medical University · Updated on 2024-11-20

60

Participants Needed

1

Research Sites

261 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study intends to explore whether the combination of Clostridium butyricum can improve the current situation of poor anti-PD1 treatment effect in patients with bladder cancer.

CONDITIONS

Official Title

PD1 Inhibitors Combined With Clostridium Butyricum for Urothelial Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • For neoadjuvant therapy: T2-T4aN0M0 bladder cancer patients
  • For adjuvant therapy: Patients with postoperative pathological stage T3-T4 and/or positive lymph node metastasis
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Patients unable to tolerate radical surgery as evaluated by researchers
  • Previous systemic chemotherapy or immunotherapy
  • Active autoimmune diseases requiring systemic treatment or other diseases needing long-term use of steroids or immunosuppressants
  • Major surgery or major trauma within 28 days before joining the study
  • Vaccination with a live vaccine within 28 days before joining the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210029

Actively Recruiting

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Research Team

X

Xiao Yang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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