Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05301816

PDN Post Market, Multicenter, Prospective, Global Clinical Study

Led by Nevro Corp · Updated on 2024-11-07

497

Participants Needed

8

Research Sites

325 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this post-market study is to evaluate the real-world experience of Nevro's Spinal Cord Stimulation (SCS) therapy in patients with chronic, intractable leg pain due to painful diabetic neuropathy (PDN). This is a multicenter, prospective, observational global study, that will partner diabetes management teams with pain physicians to provide an interdisciplinary treatment regimen for PDN patients. Outcomes will be assessed via standardized assessments.

CONDITIONS

Official Title

PDN Post Market, Multicenter, Prospective, Global Clinical Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinically diagnosed with diabetes and painful diabetic neuropathy of the lower limbs not responding to usual medical treatments
  • Average leg pain intensity of 5 or higher out of 10 on the Visual Analog Scale in the last 7 days
  • Clinical decision made to treat using Nevro Spinal Cord Stimulation including 10 kHz therapy before enrollment
  • Willing and able to provide written informed consent
  • Willing and able to follow study procedures and attend all scheduled visits
Not Eligible

You will not qualify if you...

  • Diagnosis of lower limb mononeuropathy such as causalgia or tibial/peroneal neuropathies
  • Previous lower limb amputation other than toes
  • Presence of large (3 cm or larger) or gangrenous ulcers on lower limbs
  • Medical conditions inconsistent with Nevro's SCS System guidelines or standard clinical practice
  • Other medical conditions or pain in areas not treated in this study that could interfere with study procedures or pain reporting, such as primary headache, fibromyalgia, post-herpetic neuralgia, osteoarthritis, peripheral vascular disease, or small vessel disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 8 locations

1

Neuroversion, Inc.

Anchorage, Alaska, United States, 99508

Active, Not Recruiting

2

Michigan Pain Specialists

Ann Arbor, Michigan, United States, 48108

Actively Recruiting

3

Henry Ford Health

West Bloomfield, Michigan, United States, 48322

Actively Recruiting

4

Ohio State University Wexner Medical Center

Columbus, Ohio, United States, 43210

Actively Recruiting

5

Clinical Investigations, LLC

Edmond, Oklahoma, United States, 73013

Active, Not Recruiting

6

Columbia Pain Management

Milwaukie, Oregon, United States, 97222

Actively Recruiting

7

WellSpan Interventional Pain Specialists

York, Pennsylvania, United States, 17402

Actively Recruiting

8

Virginia Interventional Pain & Spine Centers

Roanoke, Virginia, United States, 24018

Actively Recruiting

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Research Team

K

Kerry Bradley

CONTACT

M

Manish Bharara, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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