Actively Recruiting
Pectoral Block in Breast Reduction for Pain Control
Led by Carilion Clinic · Updated on 2026-04-14
80
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A reduction mammoplasty is a commonly performed procedure for patients with symptomatic macromastia. The procedure involves removing breast parenchyma for an overall reduction in breast size and to alleviate patient symptoms, such as back/neck pain, rashes in the inframammary fold, and bra strap indentation. It is well documented in the literature that this procedure has a statistically significant reduction in patient symptoms. Postoperatively, it has been within the norm to prescribe narcotics in order to alleviate post-procedural pain. Recently, however, the research realm has advocated a non-narcotic multimodal pain control (MMPC) approach to minimize narcotic usage. Narcotic use is associated with increased costs in the healthcare system due to reported heightened pain scores for extended duration, constipation, nausea, vomiting, opiate dependence among other factors associated with increased morbidity. The goal of this study is to determine if PECs II (pectoral block type II) block alone is non-inferior to the standard multimodal pain control with narcotics for postoperative pain reduction in breast reduction.
CONDITIONS
Official Title
Pectoral Block in Breast Reduction for Pain Control
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing breast reduction surgery
- Female aged over 18 and under 75 years
- Stable breast size for at least 1 year
- Persistent symptoms in at least two areas (headaches, neck pain, shoulder pain, upper back pain, painful kyphosis, bra strap discomfort, skin breakdown, upper extremity parasthesia) affecting daily activities for at least 1 year
- Documented severe breast hypertrophy with frontal and side profile photos
- Persistent pain symptoms despite at least 3 months of treatments like NSAIDs, muscle relaxants, dermatologic therapy, physical therapy, supportive devices, chiropractic care, medically supervised weight loss, or orthopedic/spine evaluation
- Breast reduction expected to reduce symptoms
- Women 50 years or older must have a negative mammogram within 2 years prior to surgery
- Weight greater than 40 kg
You will not qualify if you...
- History of chronic pain controlled with prescribed narcotics
- Primary language other than English
- No access to email or internet
- Positive pregnancy test before surgery
- Age younger than 18 or older than 75
- Weight less than 40 kg
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Carilion Clinic
Roanoke, Virginia, United States, 24014
Actively Recruiting
Research Team
P
Patrick Dugom, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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