Actively Recruiting
Pediatric Arm of DZL All Age Asthma Cohort
Led by LMU Klinikum · Updated on 2024-08-28
1500
Participants Needed
5
Research Sites
778 weeks
Total Duration
On this page
Sponsors
L
LMU Klinikum
Lead Sponsor
G
German Federal Ministry of Education and Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood. Therefore, deciphering underlying determinants for different childhood and adult asthma phenotypes is urgently needed to develop personalized treatment approaches targeting distinct underlying mechanisms. Thereby, secondary prevention early in the disease process can also be achieved. The decoding of such mechanisms and their translation to the individual patient is the aim of the Disease Area Asthma Allergy of the 'German Centre for Lung Research' (DZL).
CONDITIONS
Official Title
Pediatric Arm of DZL All Age Asthma Cohort
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Informed consent by parents (and by children if age > 8 years)
- Age between 6 months and 18 years
- Born at term (at least 37 weeks gestation)
- Active or passive understanding of German
- For children 6 months to under 6 years: more than two episodes of wheeze in the past 12 months
- For children 6 years and older: doctor-diagnosed asthma according to current guidelines
You will not qualify if you...
- Known inborn or perinatal lung disease
- Airway malformation
- Oxygen therapy after birth lasting more than 24 hours
- Ventilator support or mechanical ventilation after birth
- Diagnosis of cystic fibrosis or primary ciliary dyskinesia
- Heart failure diagnosed after birth affecting lung circulation
- Major respiratory diseases such as interstitial lung disease
- Any current non-atopic comorbidity
- Fever of at least 38.5°C (101.3°F) in the two weeks before the first visit
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
University Children's Hospital Cologne, Department of Paediatric Allergology and Pneumology
Cologne, Germany, 50937
Actively Recruiting
2
Medizinische Hochschule Hannover, Biomedical Research in Endstage and Obstructive Lung Disease
Hanover, Germany, 30625
Actively Recruiting
3
Universitaetsklinikum Schleswig-Holstein, Klinik für Kinder- und Jugendmedizin, Airway Research Center North
Lübeck, Germany, 23528
Actively Recruiting
4
Klinik für Kinder- und Jugendmedizin, Universitaetsklinikum Giessen und Marburg GmbH, Universities of Giessen and Marburg Lung Center
Marburg, Germany, 35033
Actively Recruiting
5
Klinikum der Universitaet Muenchen, Comprehensive Pulmonary Center Munich
Munich, Germany, 80337
Actively Recruiting
Research Team
E
Esther Zeitlmann, Diplom
CONTACT
B
Bianca Schaub, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here