Parental Perspectives on Pediatric Surgical Recovery: Narrative Analysis of Free-Text Comments From a Postoperative Survey.
Jessica Luo, Nicholas C West, Samantha Pang...
https://pubmed.ncbi.nlm.nih.gov/39705676Actively Recruiting
Phase Not Applicable
Age: 0Years - 18Years
All Genders
ID07095244
Pediatric Outcomes and Recovery With Peri-Operative Iron Supplement Evaluation (PORPOISE)
Led by University of British Columbia · Updated on 2026-05-14
180
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of British Columbia
Lead Sponsor
B
BC Children's Hospital Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to improve surgical outcomes for children undergoing varus-derotation osteotomy (VDRO) or pelvic osteotomy, surgeries to prevent or treat hip displacement. Many of these children have cerebral palsy or other neuromotor disorders and face a higher risk of malnutrition and iron deficiency anemia, which can increase the need for blood transfusions during surgery. The study focuses on developing a comprehensive preoperative nutritional program, including iron supplementation when needed, to reduce these risks and improve recovery. Participants aged 0 to 18 scheduled for VDRO or pelvic osteotomy will be evaluated by a dietitian and have lab tests to check for iron deficiency. Those with low iron will receive iron supplements along with dietary education and other nutrition management, while those with adequate iron will receive nutrition support without iron supplements. The study also includes a historical comparison group who had surgery without these interventions. Iron supplementation dosing and other nutritional support like vitamin supplements, tube feed optimization, and dietary education are tailored to each patient's needs. During the study, participants will be monitored through lab tests, nutrition assessments, and surveys to track adherence and family satisfaction. Researchers will measure outcomes such as the rate of blood transfusions during hospital stay, resolution of anemia, iron levels, surgical site infections, pressure wounds, and length of hospital stay. The study spans a two-year period, with follow-up up to 12 months after surgery, to assess the impact of the nutritional program on surgical recovery and overall health.
CONDITIONS
Brief Title
Pediatric Outcomes and Recovery With Peri-Operative Iron Supplement Evaluation
Who Can Participate
Age: 0Years - 18Years
All Genders
Eligibility Criteria
You may qualify if you...
- Patients scheduled for VDRO and/or pelvic osteotomy surgery (prospective cohort)
- Patients who had VDRO and/or pelvic osteotomy surgery between February 2022 and December 2024 (historical cohort)
- Ages 0 to 18 years
- Patients with or without neuromotor conditions
- Patients not enrolled in conflicting research studies
You will not qualify if you...
- Patients who had major surgery in the last 3 months
- Patients who received iron testing and treatment in the last 3 months
- Patients for whom oral or enteral iron supplements are contraindicated
- Patients with bleeding disorders
- Patients taking erythropoietin
- Patients and families unable to read and understand English (due to surveys and interviews)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Preoperative Nutritional Management
Duration - Up to surgery date (variable depending on individual scheduling)
Participants undergo comprehensive nutrition assessment and management including evaluation for iron deficiency anemia. Those with iron deficiency receive iron supplementation and education on enhancing iron intake, while all participants receive nutrition management tailored by a dietitian.
1 to 2 visits depending on nutritional needs and iron supplementation requirements
Surgery and Immediate Post-operative Care
Duration - From surgery day to hospital discharge
Participants undergo varus-derotational osteotomy (VDRO) or pelvic osteotomy surgery and receive perioperative care including monitoring for blood transfusion and surgical complications.
Hospital stay with continuous monitoring
Post-operative Follow-up and Monitoring
Duration - Up to 12 months post-surgery
Participants are monitored for resolution of anemia, iron levels, surgical site infections, pressure wounds, and recovery progress up to 12 months after surgery. Follow-up includes surveys assessing compliance, tolerance, and family satisfaction.
Periodic visits and online surveys during 12 months follow-up
Trial Site Locations
Total: 1 location
1
BC Children's Hospital
Vancouver, British Columbia, Canada, V6H 3N1
Actively Recruiting
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Research Team
S
Steffanie Fisher, MSc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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Published Research Related To This Trial
Preoperative anemia-screening clinics.
Yulia Lin
https://pubmed.ncbi.nlm.nih.gov/31808909Error traps in Pediatric Patient Blood Management in the Perioperative Period.
Gee Mei Tan, Kimmo Murto, Laura A Downey...
https://pubmed.ncbi.nlm.nih.gov/37144721Relationship Between Preoperative Anemia and In-Hospital Mortality in Children Undergoing Noncardiac Surgery.
David Faraoni, James A DiNardo, Susan M Goobie
https://pubmed.ncbi.nlm.nih.gov/27870741Iron deficiency is a public health problem in Canadian infants and children.
Dawn Hartfield
https://pubmed.ncbi.nlm.nih.gov/21731416Perioperative paediatric patient blood management: a narrative review.
Susan M Goobie, David Faraoni
https://pubmed.ncbi.nlm.nih.gov/39455307Pediatric Patient Blood Management Programs: Not Just Transfusing Little Adults.
Ruchika Goel, Melissa M Cushing, Aaron A R Tobian
https://pubmed.ncbi.nlm.nih.gov/27559005Team Approach: The Perioperative Management of Reconstructive Hip Surgery for the Non-Ambulatory Child with Cerebral Palsy and Spastic Hip Disease.
Rachel L DiFazio, Laurie J Glader, Rachel Tombeno...
https://pubmed.ncbi.nlm.nih.gov/32678539Risk factors for 90-day readmission and prolonged length of stay after hip surgery in children with cerebral palsy.
Liam R Butler, Calista L Dominy, Christopher A White...
https://pubmed.ncbi.nlm.nih.gov/36925762Preoperative anemia increases the risk of red blood cell transfusion and prolonged hospital length of stay in children undergoing spine arthrodesis surgery.
Montserrat Fontanals, James D O'Leary, Christian Zaarour...
https://pubmed.ncbi.nlm.nih.gov/30499592