Actively Recruiting

Phase 3
Age: 5Years - 19Years
All Genders
NCT07366086

Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta

Led by Amgen · Updated on 2026-05-08

71

Participants Needed

4

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary objective of this trial is to evaluate the safety of romosozumab in participants with osteogenesis imperfecta (OI) that have completed Study 20200105, regardless of whether they received investigational product (romosozumab) until the last protocol-specified dose or ended investigational product early.

CONDITIONS

Official Title

Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta

Who Can Participate

Age: 5Years - 19Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant has provided informed consent/assent prior to trial activities, or legally authorized representative has provided consent with participant assent as per local regulations
  • Participant was randomized to the romosozumab arm and completed Trial 20200105 through the Month 15 Visit, regardless of whether they received all protocol-specified doses or ended treatment early
Not Eligible

You will not qualify if you...

  • Currently receiving treatment in another investigational device or drug trial, or less than 2 years since ending treatment on other investigational trials except Trial 20200105
  • Participant likely to be unavailable to complete all protocol-required visits or comply with required trial procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Indiana University

Indianapolis, Indiana, United States, 46202

Actively Recruiting

2

Universitaetsklinikum Koeln

Cologne, Germany, 50937

Actively Recruiting

3

Universitaetsklinikum Wuerzburg

Würzburg, Germany, 97074

Actively Recruiting

4

Okayama Saiseikai Outpatient Center Hospital

Okayama, Okayama-ken, Japan, 700-0013

Actively Recruiting

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Research Team

A

Amgen Call Center

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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