Actively Recruiting
Pilot Randomized Pediatric RISE (Resource Intervention to Support Equity) Feasibility Study
Led by Dana-Farber Cancer Institute · Updated on 2026-02-10
40
Participants Needed
4
Research Sites
N/A
Total Duration
On this page
Sponsors
D
Dana-Farber Cancer Institute
Lead Sponsor
A
American Cancer Society, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the PediRISE program, a support intervention for poverty-exposed families with children newly diagnosed with cancer or undergoing hematopoietic stem cell transplant (HSCT). This pilot, multi-center, randomized study aims to determine if families are interested in participating and whether the program can be feasibly delivered alongside usual care. The study is supported by grants from the American Cancer Society and the Children's Cancer Research Fund. Participants will be randomly assigned to one of two groups: the PediRISE Program Group or the Usual Care Group. The PediRISE program includes twice-monthly cash transfers delivered via debit card or digital payment methods, benefits counseling to help maintain access to support programs, and standard supportive care from social workers or resource specialists. The Usual Care Group receives standard supportive care without the additional PediRISE interventions. Program orientation and surveys are completed in-person, by phone, or virtually, with the study lasting about six months. During the study, parents or guardians will complete baseline and end-of-study surveys and have optional meetings with benefits counselors. Researchers will monitor participation rates and retention over six months to assess feasibility. The study involves screening, study visits, and questionnaires to collect data on family engagement and program impact. A total of approximately 40 pediatric participants and their families are expected to join, with ongoing support and follow-up provided throughout the study period.
CONDITIONS
Brief Title
PediRISE Feasibility
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Child diagnosed with new cancer and receiving front-line cancer therapy
- Child under 18 years old at enrollment
- Family reports low income below 200% of the federal poverty level
- Family lives in CA, CT, MA, ME, NH, NJ, NY, or RI
- Child has established care and started cancer therapy within prior 2 months
- Child planned for at least 4 months of cancer therapy at study site
- Provider approval to approach family
- OR child undergoing allogeneic HSCT for cancer treatment
- Child planned to receive follow-up care at study site after HSCT
You will not qualify if you...
- Planned transfer to a non-study facility for cancer therapy
- Foreign national family receiving care as Embassy-pay patient
- Child enrolled in other clinical drug trials with overlapping poverty data aims
- Child or household member receiving Supplemental Security Income (SSI)
- Child previously received the RISE intervention (HSCT cohort only)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person, by telephone, or virtual)
Duration - 6 months
Participants randomized to the PediRISE Program Group receive twice-monthly cash transfers and benefits counseling to support their family during cancer treatment. Participants randomized to the Usual Care Group receive standard supportive care from social workers or resource specialists. All participants complete baseline and end of study surveys.
Baseline orientation plus regular contact for twice-monthly cash transfers and support
Trial Site Locations
Total: 4 locations
1
University of California San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
2
Boston Children's Hospital
Boston, Massachusetts, United States, 02215
Actively Recruiting
3
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
4
Columbia University Medical Center
New York, New York, United States, 10032
Actively Recruiting
Research Team
K
Kira Bona, MD, MPH
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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