Actively Recruiting
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
Led by University of Pittsburgh · Updated on 2026-01-07
470
Participants Needed
14
Research Sites
164 weeks
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.
CONDITIONS
Official Title
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 16 to 30 years at time of enrollment
- Diagnosis of sickle cell disease of any genotype based on referral or documentation
- Reports chronic pain 4 or more days per week for the past 3 months or more, OR
- Being prescribed pain medication to be taken 4 or more days per week for the past 3 months or more, OR
- Taking pain medication 4 or more days per week for the past 3 months or more, OR
- Receiving non-pharmaceutical pain treatment 4 or more days per week for the past 3 months or more
- Access to an iOS or Android mobile device with internet access
You will not qualify if you...
- Unable to speak or read English
- Prior hematopoietic stem cell transplant for sickle cell disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
University of South Alabama Medical Center
Mobile, Alabama, United States, 36617
Actively Recruiting
2
UCLA Mattel Children's Hospital Ronald Reagan Hospital
Los Angeles, California, United States, 90095
Actively Recruiting
3
Connecticut Children's Medical Center
Hartford, Connecticut, United States, 06106
Actively Recruiting
4
Children's Healthcare of Atlanta
Atlanta, Georgia, United States, 30345
Actively Recruiting
5
Ann and Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, United States, 60611
Actively Recruiting
6
The Regents of the University of Michigan
Ann Arbor, Michigan, United States, 48109-1079
Actively Recruiting
7
Rutgers New Jersey Medical School
Newark, New Jersey, United States, 07103
Actively Recruiting
8
Weil Cornell Medical College
New York, New York, United States, 10065
Actively Recruiting
9
University of Rochester Medical Center
Rochester, New York, United States, 14642
Actively Recruiting
10
Wake Forest Baptist Hospital
Durham, North Carolina, United States, 27106
Actively Recruiting
11
East Carolina University Health Medical Center
Greenville, North Carolina, United States, 27834
Actively Recruiting
12
UPMC University of Pittsburgh Classical Hematology Adult Clinic
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
13
UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15224
Actively Recruiting
14
Virginia Commonwealth University
Richmond, Virginia, United States, 23284
Actively Recruiting
Research Team
S
Steffi Siebert, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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