Ultrasound-guided local infiltration analgesia for hip surgery: myth or reality?
Romualdo Del Buono, Giuseppe Pascarella, Fabio Costa...
https://pubmed.ncbi.nlm.nih.gov/31124626Actively Recruiting
Led by ASST Gaetano Pini-CTO · Updated on 2025-12-10
100
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating a new local anesthesia technique compared to standard spinal anesthesia for adults undergoing hip endoprosthesis surgery due to femoral fracture. The study aims to find out if the new motor-sparing method controls pain as effectively as spinal anesthesia during the first two days after surgery and whether it helps participants move their leg sooner. This approach targets sensory nerves around the hip to reduce pain while potentially avoiding side effects like nausea and allowing faster recovery. Participants will be randomly assigned to one of two groups. One group will receive the new anesthesia technique involving three ultrasound-guided injections: an anterior Pericapsular Nerve Group (A-PENG) block, local infiltration analgesia (LIA) around the incision, and a posterior PENG (PONG) block. The other group will receive the standard spinal anesthesia before surgery. All participants will receive standardized post-operative pain treatment including intravenous paracetamol, ketorolac, and morphine via patient-controlled analgesia. During the study, researchers will monitor the amount of additional pain medication used within 48 hours after surgery and assess participants' ability to move their hip, knee, and foot soon after the operation. They will also track nausea, pain intensity, and length of hospital stay. Data will be securely collected and analyzed to compare outcomes between groups. Participation involves follow-up visits and assessments up to 48 hours post-surgery, with hospital stay monitored up to 30 days.
CONDITIONS
PENG Block + LIA For Endoprosthesis Surgery With Anterior Approach
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants receive either a motor-sparing anesthetic technique consisting of three ultrasound-guided injections before surgery or standard spinal anesthesia according to the center's standard practice.
1 visit (in-person)
Duration - 48 hours
Participants are monitored for pain, limb mobility, nausea, and other outcomes for up to 48 hours after surgery with a standardized pain management protocol.
Continuous monitoring during hospital stay, including assessments upon arrival in the Post-Anesthesia Care Unit and up to 48 hours post-surgery
Duration - Up to 30 days
Participants continue to be observed until hospital discharge to assess length of hospital stay and recovery.
Hospital visits as part of routine care until discharge
Total: 1 location
1
Gaetano Pini-CTO
Milan, Italy, 20122
Actively Recruiting
R
Romualdo Del Buono, MD
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Romualdo Del Buono, Giuseppe Pascarella, Fabio Costa...
https://pubmed.ncbi.nlm.nih.gov/31124626Romualdo Del Buono, Eleonora Padua, Giuseppe Pascarella...
https://pubmed.ncbi.nlm.nih.gov/33432791Romualdo Del Buono, Giuseppe Pascarella, Eleonora Padua...
https://pubmed.ncbi.nlm.nih.gov/34263587Romualdo Del Buono, Eleonora Padua, Giuseppe Pascarella...
https://pubmed.ncbi.nlm.nih.gov/34337929Romualdo Del Buono, Eleonora Padua, Giuseppe Pascarella...
https://pubmed.ncbi.nlm.nih.gov/34527412Romualdo Del Buono, Andrea Tognù
https://pubmed.ncbi.nlm.nih.gov/38980297Laura Girón-Arango, Philip W H Peng, Ki Jinn Chin...
https://pubmed.ncbi.nlm.nih.gov/30063657