Actively Recruiting

Phase Not Applicable
Age: 65Years - 100Years
All Genders
NCT07288983

PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery

Led by Poznan University of Medical Sciences · Updated on 2026-03-04

93

Participants Needed

1

Research Sites

51 weeks

Total Duration

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AI-Summary

What this Trial Is About

This randomized, double-blinded, controlled clinical trial compares three motor-sparing regional anesthesia techniques used for postoperative analgesia in patients undergoing hip arthroplasty: the Pericapsular Nerve Group (PENG) block, the suprainguinal Fascia Iliaca Compartment Block (S-FICB), and the Lumbar Erector Spinae Plane Block (L-ESPB). Although all three techniques are widely used in modern hip surgery, their relative analgesic efficacy, opioid-sparing potential, and impact on early functional recovery have not been directly compared in a single study. The primary objective is to determine which block provides the most effective postoperative analgesia while preserving motor function and facilitating early mobilization. Secondary objectives include comparisons of opioid consumption, pain scores at rest and during movement, time to first rescue analgesia, block-related adverse events, quadriceps strength, incidence of postoperative nausea and vomiting, and early functional outcomes. This study aims to identify the optimal motor-sparing regional anesthesia strategy for older adults undergoing hip arthroplasty.

CONDITIONS

Official Title

PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery

Who Can Participate

Age: 65Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 65 years or older scheduled for elective hip arthroplasty under spinal anesthesia
  • Ability to provide written informed consent
  • Ability to understand and use numerical pain rating scales (0-10)
  • ASA physical status II or III
  • Expected hospital stay of at least 48 hours after surgery for data collection
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent due to cognitive, language, hearing, or speech limitations
  • Coagulopathy or anticoagulation therapy not safe for regional anesthesia
  • Infection at planned nerve block site
  • Allergy or contraindication to ropivacaine, local anesthetics, or study drugs
  • Pre-existing neurological deficits in lower limbs affecting assessments
  • Severe spinal deformity or anatomical issues preventing safe nerve block
  • Chronic opioid use exceeding 30 mg oral morphine equivalents daily for over 2 weeks
  • Severe kidney failure (eGFR <30) or severe liver impairment
  • Uncontrolled diabetes (fasting glucose >300 mg/dL or HbA1c >10%)
  • History of local anesthetic systemic toxicity (LAST)
  • Participation in another interventional trial within 30 days
  • Any condition interfering with study adherence, safety, or outcome reliability

AI-Screening

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Trial Site Locations

Total: 1 location

1

Poznan University of Medical Sciences

Poznan, Poland, 62-701

Actively Recruiting

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Research Team

M

Malgorzata Reysner, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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