Comparing Penile Skin and Buccal Mucosal Grafts for Long Anterior Urethral Stricture Surgery A Randomized Study

What this Trial Is About

The trial investigates two surgical methods for treating long segment bulbar urethral stricture, a condition involving narrowing of the urethra. Researchers aim to compare the outcomes of dorsal onlay buccal mucosal graft BMG versus penile skin graft PSG urethroplasty, both established techniques used to manage this challenging condition. The study is a prospective randomized evaluation sponsored by Tanta University to assess surgical success and related outcomes. Participants will undergo one of two types of dorsal onlay augmentation urethroplasty under spinal or general anesthesia. One group receives a buccal mucosal graft harvested from the inner cheek, which is sutured dorsally over the strictured urethral segment after removing fibrotic tissue. The other group receives a penile skin graft taken from the ventral surface of the penis, also applied dorsally after excision of the fibrotic area. Both procedures focus on reconstructing the urethra to relieve the stricture. During the study, participants will be monitored for surgical success at 9 months after surgery, which is the primary outcome. Secondary measures include symptom assessment using the International Prostate Symptom Score IPSS, the length of the urethral stricture measured during surgery, and any postoperative complications up to 9 months. The study involves random assignment to either surgical technique and does not use blinding.

Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture