Actively Recruiting

Phase 2
Age: 18Years - 70Years
All Genders
NCT06998628

Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis

Led by Tanta University · Updated on 2025-09-10

50

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

Sponsors

T

Tanta University

Lead Sponsor

P

Prof. Sahar Kamal Hegazy, Professor of Clinical Pharmacy, Faculty of Pharmacy - Tanta University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Rheumatoid arthritis (RA) is a long-term inflammatory condition that leads to gradual damage of joints lined by synovial membranes, along with various potential effects outside of the joints. While RA can affect any joint, it typically involves the metacarpophalangeal, proximal interphalangeal, and metatarsophalangeal joints, as well as the wrists and knees. Symptoms related to the joints and surrounding tissues include swelling, tenderness upon touch, morning stiffness, and significant difficulty moving the affected joints

CONDITIONS

Official Title

Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with active rheumatoid arthritis (not in remission) confirmed by ACR/EULAR criteria with DAS28 score above 2.6
  • Patients currently receiving conventional DMARDs
  • Both male and female patients
  • Age between 18 and 70 years old
Not Eligible

You will not qualify if you...

  • History of retinal or cerebral hemorrhage
  • Renal (kidney) or hepatic (liver) dysfunction
  • Known hypersensitivity to the study medications
  • Pregnant or breastfeeding women
  • Patients currently using biological or synthetic DMARDs

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Medicine, Al-Azhar University

Damietta, Damietta Governorate, Egypt, 34511

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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