Actively Recruiting
Pentoxifylline in Patients With Ulcerative Colitis
Led by Ihab Elsayed Hassan · Updated on 2026-04-15
60
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ulcerative colitis (UC) is a persistent, idiopathic form of inflammatory bowel disease (IBD) marked by uninterrupted inflammation of the colon's mucosal lining, usually starting at the rectum and progressing proximally in a continuous manner. It manifests clinically with recurrent episodes of abdominal pain, bloody diarrhea, urgency, tenesmus, and weight loss. The precise cause of UC is still unknown; however, it is thought to arise from a multifactorial interaction involving genetic susceptibility, immune system dysregulation, disturbances in gut microbiota composition, and various environmental factors.
CONDITIONS
Official Title
Pentoxifylline in Patients With Ulcerative Colitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 218 years
- Both male and female participants are eligible
- Negative pregnancy test and use of effective contraception for women of childbearing potential
- Diagnosed with mild or moderate ulcerative colitis
You will not qualify if you...
- Currently breastfeeding
- Significant abnormalities in liver or kidney function
- Diagnosis of diabetes mellitus
- History of colorectal cancer
- Severe ulcerative colitis
- Use of rectal or systemic steroids
- Use of immunosuppressive or biological therapies
- Addiction to alcohol or drugs
- Known allergy to pentoxifylline or mesalamine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fayoum University
Al Fayyum, Egypt, 54687
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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