Actively Recruiting
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
Led by Oulu University Hospital · Updated on 2025-08-05
3000
Participants Needed
1
Research Sites
1037 weeks
Total Duration
On this page
Sponsors
O
Oulu University Hospital
Lead Sponsor
P
PerkinElmer, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a Finnish general population. Condition or disease: pre-eclampsia, intrauterine growth restriction, polycystic ovary syndrome
CONDITIONS
Official Title
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant women in their first trimester
- Understands Finnish
- 18 years or older
- Signed informed consent
- Participates in PEPPI-study with blood samples taken at first and third trimester
- Permits blood sampling from the umbilical cord when the baby is born
- Biological father to the child born for the mother who participated in PEPPI study
- Signed informed consent for fathers
- Child born to mother who participated in PEPPI study
- Signed informed consent from parent(s) for children
- Mother in risk, control, or PCOS group with ultrasound at 30-32 weeks or mother who developed pre-eclampsia
- Signed informed consent for FERPPI-study
- Child has blood samples taken at birth and at 3 months of age
You will not qualify if you...
- Multiple pregnancy
- Miscarriage or termination of the index pregnancy
- No first trimester blood sampling
- No blood samples at first or third trimester
- No umbilical cord blood sample after baby is born
- Fathers who do not understand Finnish
- No consent from parent(s) for children
- Mother or father declines participation in offspring study
- No blood samples from mother or child for FERPPI-study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Wellbeing Services County of North Ostrobothnia
Oulu, Finland, 90100
Actively Recruiting
Research Team
J
Jaana E Nevalainen, Assoc prof
CONTACT
T
Terhi Piltonen, Professor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
6
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