Actively Recruiting

Phase Not Applicable
Age: 19Years - 75Years
All Genders
Healthy Volunteers
NCT06783660

PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction

Led by NIBEC Co., Ltd. · Updated on 2025-10-03

114

Participants Needed

1

Research Sites

59 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This clinical trial aims to compare the efficacy and safety of applying "PeptiCol EZgraft" in extraction socket preservation procedures against "Regenomer," in terms of reducing the amount of alveolar bone change during the healing process following tooth extraction.

CONDITIONS

Official Title

PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction

Who Can Participate

Age: 19Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 19 to 75 years
  • Systemically healthy or with mild systemic disease (ASA I or II)
  • Planning to place implants in the upper or lower jaw after tooth extraction
  • Extraction socket with at least 50% of alveolar bone wall remaining
  • Willing to maintain good oral hygiene during the trial
  • Voluntarily agree to participate and sign informed consent
  • Willing to comply with all trial procedures for the entire duration
Not Eligible

You will not qualify if you...

  • Extensive alveolar bone loss in the extraction socket area
  • Severe gum disease or acute periodontal abscess
  • Poor oral hygiene
  • History of bone grafts or implants in the treatment area
  • Mucosal diseases caused by autoimmune disorders
  • Known allergy to collagen products
  • Smoking more than 10 cigarettes daily
  • Alcohol or drug addiction (screened with AUDIT-K)
  • Use of bone-affecting drugs within 2 weeks before screening
  • Use of rheumatic or immunosuppressant drugs within 2 weeks before screening
  • Long-term use (over 12 weeks) of bisphosphonates for osteoporosis
  • Uncontrolled bleeding disorders or use of blood-thinning medications
  • Uncontrolled diabetes or high blood pressure
  • Significant cardiovascular, gastrointestinal, respiratory, endocrine, or nervous system diseases
  • Immune disorders including AIDS
  • Pregnant or breastfeeding women
  • Participants of childbearing potential must use contraception during the trial and for 16 weeks after

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Seoul National University Dental Hospital

Korea, Seoul, South Korea, 03080

Actively Recruiting

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Research Team

P

Park Shin young

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction | DecenTrialz