Evaluating Safety and Effectiveness of PeptiCol EZgraft Compared to Regenomer for Preserving Bone After Tooth Extraction

What this Trial Is About

Researchers are evaluating the safety and effectiveness of PeptiCol EZgraft compared to Regenomer in preserving the alveolar bone after tooth extraction. The study focuses on whether PeptiCol EZgraft better reduces bone changes during healing, aiming to minimize alveolar bone loss following the extraction procedure. Participants will receive either a peptide-loaded collagen sponge combined with collagen gel PeptiCol EZgraft or a collagen sponge Regenomer placed in the extraction socket after tooth removal. The trial is open-label and randomized, with treatment applied immediately after extraction to support bone preservation. During the 4-month study, participants will undergo CBCT imaging to measure changes in alveolar bone width and be monitored for any adverse events related to the devices used. Participant satisfaction and bone healing will also be evaluated. Safety assessments will occur at each visit, and the total participation lasts through the 4-month follow-up period.

PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction