Actively Recruiting

Phase 4
Age: 45Years - 99Years
All Genders
NCT05440240

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Led by Regionshospitalet Silkeborg · Updated on 2023-05-17

400

Participants Needed

1

Research Sites

372 weeks

Total Duration

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AI-Summary

What this Trial Is About

Comparing percutaneous needle fasciotomy +/- corticosteroid injection for Dupuytren's contracture affecting metacarpophalangeal joints. A clinician-initiated, multicenter, randomized controlled trial.

CONDITIONS

Official Title

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Who Can Participate

Age: 45Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Dupuytren contracture with at least 20° passive extension deficit in the metacarpophalangeal joint measured by goniometer
  • Contracture affecting fingers II through V
  • Presence of a well-defined or palpable cord
  • Successful correction of MCP joint during PNF treatment to less than 20° passive extension deficit
Not Eligible

You will not qualify if you...

  • Legally incapacitated individuals
  • Previous participation in this study with another finger ray
  • Contracture limited to proximal or distal interphalangeal joints with less than 20° deficit in MCP joint
  • Previous hand surgery on the affected finger
  • Known allergy to the study medications
  • Use of anticoagulant therapy (except acetylsalicylic acid)
  • Pregnant or lactating individuals
  • Insulin-dependent diabetes mellitus
  • Ongoing systemic or local infection at the procedure site
  • Rheumatoid arthritis
  • Amyloidosis or mucopolysaccharidosis
  • Inability to communicate, cooperate, or participate in follow-up

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Silkeborg Regional Hospital

Silkeborg, Denmark, 8600

Actively Recruiting

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Research Team

L

Laura H Matthiesen, MS, PhD-student

CONTACT

J

Jeppe Lange, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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