Actively Recruiting

Age: 18Years +
All Genders
ID05067543

Perform Humeral System Study for Shoulder Arthroplasty Using the Tornier Perform Humeral Stem Device

Led by Stryker Trauma and Extremities · Updated on 2026-02-20

300

Participants Needed

10

Research Sites

22 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to collect safety and performance data on the PERFORM20 Humeral System, a device used for partial or total shoulder replacement in patients with conditions such as osteoarthritis, avascular necrosis, post-traumatic arthrosis of the shoulder region, and rotator cuff tear arthropathy. It is an international, single-arm, multicenter, prospective post-market clinical follow-up study designed to evaluate patient outcomes over time. The study focuses on patient-reported measures related to quality of life, pain, and function, as well as safety and radiographic assessments. Participants will undergo shoulder arthroplasty using the Tornier Perform Humeral Stem device. Data will be collected at baseline, during surgery, immediately after surgery, and then annually for up to 10 years post-operation. The study monitors the device's safety and performance through various assessments including patient satisfaction and radiological imaging throughout the follow-up period. During the study, participants will be assessed using patient-reported outcome measures such as ASES, Constant Murley, SANE, Subject Satisfaction, and EQ-5D scores from baseline through follow-up visits up to 10 years. Researchers will also track adverse events, revision surgeries, and imaging evaluations of the shoulder. The study involves long-term monitoring to understand the safety and effectiveness of the implant over time.

CONDITIONS

Brief Title

Perform Humeral System Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older at the time of informed consent or non-opposition when applicable
  • Willing and able to sign an informed consent form approved by IRB or EC when applicable
  • Willing and able to comply with study protocol requirements
  • Considered a candidate for shoulder arthroplasty using the study device
  • Meets indications for use or other local, regional, or geographic regulatory requirements
Not Eligible

You will not qualify if you...

  • Unable to comply with study procedures (e.g., cannot understand study questions or keep assessment schedules)
  • Belongs to a vulnerable group (minors, legally incapacitated, or others subject to coercion)
  • Active local or systemic infection, sepsis, or osteomyelitis
  • Poor bone quality risking prosthesis migration or fracture
  • Significant injury to the brachial plexus
  • Inadequate bone stock in proximal humerus or glenoid fossa
  • Neuromuscular disease such as joint neuropathy
  • Known allergy to product materials
  • Metabolic disorders impairing bone formation
  • Pregnancy
  • Planned for two-stage surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Implementation

Duration - Day of surgery

Participants undergo partial or total shoulder arthroplasty using the Tornier Perform Humeral Stem device.

1 surgical visit (in-person)

Long-term Monitoring

Duration - Up to 10 years post-implantation

Participants are followed to assess safety, device performance, and quality of life through patient-reported outcome measures and radiographic assessments.

Regular follow-up visits over 10 years

Trial Site Locations

Total: 10 locations

1

Baptist Healthcare

Lexington, Kentucky, United States, 40503

Actively Recruiting

2

Summit Orthopedics

Eagan, Minnesota, United States, 55121

Actively Recruiting

3

Mayo Clinic

Rochester, Minnesota, United States, 55905

Terminated

4

Washington University

St Louis, Missouri, United States, 63110

Active, Not Recruiting

5

Orthopedic Institute

Sioux Falls, South Dakota, United States, 57105

Actively Recruiting

6

University of Utah

Salt Lake City, Utah, United States, 84108

Actively Recruiting

7

Roth McFarlane Hand and Upper Limb Centre

London, Ontario, Canada, N6A 4L6

Active, Not Recruiting

8

Orthopedic Center Santy

Lyon, France, 69008

Active, Not Recruiting

9

Schulthess Klinik

Zurich, Switzerland, CH-8008

Active, Not Recruiting

10

Wrightington Hospital

Wigan, Lancashire, United Kingdom, WN6 9EP

Active, Not Recruiting

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Research Team

M

Meredith Schreier

A

Amjad Uneisi

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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