Actively Recruiting

Age: 50Years +
All Genders
ID06742671

Performance of a Fast-track Pathway for Giant Cell Arteritis Diagnosis

Led by Groupe Hospitalier de la Rochelle Ré Aunis · Updated on 2025-06-20

100

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Giant Cell Arteritis (GCA) is an inflammation of artery walls mainly affecting people over 50 years old. The diagnosis can be difficult due to non-specific symptoms like headaches, jaw pain, and scalp tenderness, but it is important to diagnose quickly to avoid serious complications such as vision loss or stroke. Advances in ultrasound technology have improved early diagnosis by identifying a characteristic "halo" sign on temporal arteries, potentially reducing the need for biopsies. This research evaluates a fast-track diagnostic pathway designed to speed up the diagnosis of GCA. Patients suspected of having GCA undergo ultrasound exams of temporal and axillary arteries. If inflammation is seen on both sides, biopsy may be avoided. If ultrasound is negative or inconclusive, biopsy is performed. This approach aims to reduce diagnosis time from about 10 days to just one day and to minimize hospital stays and biopsies. Participants suspected of GCA will be assessed through clinical signs, ultrasound imaging, and if needed, biopsy. Researchers will measure the time from initial suspicion to ultrasound results and corticosteroid treatment start. They will also track cases with alternative diagnoses and compare ultrasound and biopsy findings. The study continues until March 2027 and seeks to improve early diagnosis and care for people with this condition.

CONDITIONS

Brief Title

Performance of a Fast-track Pathway for Giant Cell Arteritis Diagnosis

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient suspected of Giant Cell Arteritis (GCA)
Not Eligible

You will not qualify if you...

  • Opposition to the use of their data

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
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3
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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 7 days

Participants suspected of Giant Cell Arteritis undergo ultrasound and may have biopsies to confirm diagnosis.

1 to 2 visits depending on ultrasound and biopsy results

Long-term Monitoring

Duration - Up to 1 month

Participants are followed up to assess final diagnosis and treatment outcomes.

1 follow-up visit

Trial Site Locations

Total: 1 location

1

Groupe Hospitalier de la Rochelle Ré Aunis

La Rochelle, France

Actively Recruiting

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Research Team

C

Caroline Allix-Béguec, Ph.D.

C

Cécile Duchiron, Ph.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Diagnostic Strategy Using Color Doppler Ultrasound of Temporal Arteries in Patients With High Clinical Suspicion of Giant Cell Arteritis : A Prospective Cohort Study.

Guillaume Denis, Olivier Espitia, Caroline Allix-Béguec...

https://pubmed.ncbi.nlm.nih.gov/38710093