Actively Recruiting
Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study
Led by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Updated on 2022-05-02
62
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a single center, prospective, observational study to explore and evaluate the differences on cognitive function and brain function by functional-MRI in autonomous cortisol secretion patients, and the different treatments methods on the cognitive function and brain function in patients with autonomous cortisol secretion
CONDITIONS
Official Title
Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 20 to 65 years
- At least 6 years of education
- Right-handed
- Able to complete all cognitive function tests
- Have adrenal lesions 1 cm or larger in diameter
- Diagnosed with non-functioning adrenal adenomas
- Diagnosed with autonomous cortisol secretion
You will not qualify if you...
- Less than 6 years of education
- Younger than 20 years or older than 65 years
- Adrenal incidentaloma less than 1 cm in diameter
- Active malignancies
- History of thyroid disease
- Recent acute infection within the last month
- Central nervous system diseases such as brain trauma, intracranial hemorrhage, or stroke
- Contraindications to MRI such as metal implants or claustrophobia
- Adrenal tuberculosis
- Suspected or diagnosed adrenocortical carcinoma
- Unable to complete all cognitive function tests
- Use of steroids or drugs affecting steroid metabolism in the past 3 months
- Clinical Cushing syndrome
- Cushing disease
- Primary hyperaldosteronism
- Pheochromocytoma
- Severe impairment of heart, liver, kidney or other organs
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Endocrinology, Drum Tower Hospital affiliated to Nanjing University Medical School
Nanjing, Jiangsu, China, 210008
Actively Recruiting
Research Team
D
Dalong Zhu, MD,PhD
CONTACT
P
PIng Li, MD,PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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