Actively Recruiting

Phase Not Applicable
Age: 18Years - 89Years
All Genders
NCT02662751

Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA

Led by Centre Hospitalier Universitaire de Nīmes · Updated on 2025-03-10

260

Participants Needed

2

Research Sites

346 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main objective of this study is to compare two post-stroke/TIA (transient ischemic attack) imaging strategies in terms of the number of clinically important (i.e. requiring specific treatment according to current recommendations) lesions detected. The first strategy is the current/usual strategy in each participating centre and the second strategy consists in starting the post-stroke/TIA imaging assessment by a whole-body, low-dose angiography and subsequently resorting to elements of the usual strategy if required.

CONDITIONS

Official Title

Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA

Who Can Participate

Age: 18Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient informed about the study, its objectives, constraints, and rights
  • Patient has given free and informed consent and signed the consent form
  • Patient is affiliated with or beneficiary of a health insurance plan
  • Patient is available for 36 months of follow-up
  • Patient had a stroke within the past 10 days confirmed by MRI with a diffusion sequence or a transient ischemic attack (TIA) within the past 10 days with an ABCD2 score greater than 3 and no hemorrhage
Not Eligible

You will not qualify if you...

  • Current or recent participation in another biomedical research study within the past 3 months or during an exclusion period
  • Patient under guardianship or judicial protection
  • Refusal to sign the consent form
  • Inability to properly inform the patient or trusted person about the study
  • Pregnancy, parturition, or breastfeeding
  • Contraindication to treatments used in this study
  • Known allergy to contrast medium or severe allergy to iodine
  • Known active cancer or history of cancer treatment
  • Full body CT scan in the previous 3 months
  • Renal failure with creatinine clearance below 60 ml/min
  • Monoclonal immunoglobulin
  • History of severe symptomatic cardiovascular events (myocardial infarction, aortic dissection, mesenteric ischemia, renal ischemia)
  • Emergency situations preventing the planned course of the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

CHRU de Montpellier - Hôpital Gui de Chauliac

Montpellier, France, 34295

Actively Recruiting

2

CHRU de Nîmes - Hôpital Universitaire Carémeau

Nîmes, France, 30029

Not Yet Recruiting

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Research Team

F

Francesco Macri, MD

CONTACT

C

Carey Suehs, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

2

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