Actively Recruiting

Phase Not Applicable
Age: 2Years - 12Years
All Genders
NCT06967675

Perfusion Index in Pediatric Low-Flow Anesthesia

Led by Istinye University · Updated on 2025-07-10

90

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia. PI will be monitored at multiple intraoperative and postoperative time points to assess its relationship with hemodynamic stability and depth of anesthesia. The study will also investigate whether low-flow anesthesia affects the incidence of emergence agitation (EA). Patients will be assigned to either low-flow or normal-flow anesthesia groups based on routine clinical practice. No intervention will be applied beyond standard care. The findings are expected to provide insight into the predictive value of PI in postoperative recovery and support safer anesthesia practices in pediatric populations.

CONDITIONS

Official Title

Perfusion Index in Pediatric Low-Flow Anesthesia

Who Can Participate

Age: 2Years - 12Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • ASA I-II pediatric patients
  • Age 2 to 12 years
  • Undergoing elective surgery lasting between 1 to 6 hours
  • Informed consent obtained from parents or guardians
Not Eligible

You will not qualify if you...

  • Cardiovascular, respiratory, neurological, metabolic, or endocrine disorders
  • Premature birth with corrected age less than 2 years
  • Obesity or severe malnutrition (BMI below 5th or above 95th percentile)
  • Psychiatric or neurodevelopmental disorders such as autism
  • Malignant hyperthermia or hypersensitivity to anesthetics
  • Emergency surgeries
  • Lack of IV access requiring inhalational induction
  • Contraindications to low-flow anesthesia including severe pulmonary disease, congenital heart disease with shunt physiology, anticipated high oxygen demand, airway obstruction risk
  • Surgeries requiring high gas flow or lasting more than 6 hours

AI-Screening

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Trial Site Locations

Total: 1 location

1

Istinye Üniversity

Istanbul, Merkez Mahallesi, Turkey (Türkiye), 34250

Actively Recruiting

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Research Team

I

ilke dolgun

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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