Actively Recruiting
PeRfusiOn Post tHrombEcTomy (PROPHET)
Led by Insel Gruppe AG, University Hospital Bern · Updated on 2024-11-15
279
Participants Needed
2
Research Sites
173 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Endovascular mechanical thrombectomy is the standard of care for treating patients with a large-vessel occlusion acute ischemic stroke. However, in more than half of these patients, remaining distal vessel occlusions limit the benefit of this therapy. Currently the detection of residual vessel occlusions and the decision for further treatment by the operator is based on the 2D digital subtraction angiography (DSA) images. However, this technique has several limitations. Recently, a new imaging technique, with the possibility to acquire 3D time-resolved perfusion images directly in the operating room was introduced (the flat-panel detector computed tomography perfusion imaging, FDCTP). It can overcome the spatial limitations of 2D DSA, but the details on clinical validation and utility of FDCTP are currently lacking.
CONDITIONS
Official Title
PeRfusiOn Post tHrombEcTomy (PROPHET)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent is provided
- Patient underwent mechanical thrombectomy or was intended for endovascular treatment but only received diagnostic angiography
- FDCTP imaging was performed as part of clinical care
You will not qualify if you...
- Unable to give informed consent due to insufficient knowledge of the study language
- Unable to attend the clinically indicated 90-day follow-up visit after the stroke (e.g., living abroad)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University Hospital Basel
Basel, Switzerland, 4031
Not Yet Recruiting
2
University Hospital Bern
Bern, Switzerland, 3010
Actively Recruiting
Research Team
J
Johannes Kaesmacher, Prof.
CONTACT
S
Seraina Beyeler, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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