Actively Recruiting
Surgical Treatment of Peri-implantitis Comparing Open Flap Debridement With and Without Implantoplasty
Led by University of Oslo · Updated on 2026-04-29
35
Participants Needed
2
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are studying the treatment of peri-implantitis, a condition affecting dental implants, to compare the effects of two surgical methods. This randomized, controlled trial evaluates whether adding implantoplasty—a procedure that smooths the rough titanium surface of implants—improves outcomes when combined with open flap debridement. The study is conducted at a single center and includes adult participants with peri-implantitis on at least two implants. Participants receive surgical treatment involving open flap debridement with or without implantoplasty. Implantoplasty is aimed at facilitating better oral hygiene by mechanically smoothing the implant surfaces. The trial has two treatment groups: one group will have open flap debridement plus implantoplasty, while the other group will have open flap debridement alone. Both procedures are performed surgically. During the study, participants will be monitored for bleeding on probing, suppuration, pocket probing depth, clinical attachment loss, radiographic bone loss, and implant fractures at 12 and 24 months after treatment. Quality of life changes reported by patients will also be assessed before treatment and at 24 months. The study involves double-blind evaluation and randomized allocation, with follow-ups extending up to two years to assess the long-term effects of the treatments.
CONDITIONS
Brief Title
Peri-implantitis Implantoplasty Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Peri-implantitis on at least two implants with similar surface and defect type
- Able to provide informed consent
- Exposed, modified implant surface with bone loss greater than 2 mm
You will not qualify if you...
- Previous radiotherapy to the jaws, current chemotherapy, or systemic long-term corticosteroid treatment
- Past or present use of bisphosphonate treatment
- Pregnant or nursing
- Patients classified as higher than class II according to ASA classification
- Implant not available for implantoplasty treatment
- Unable to understand or respond to quality of life questionnaire
- Implant placement considered suboptimal and a major factor in peri-implantitis development
- History of peri-implantitis surgery within 6 months prior to screening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo surgical treatment of peri-implantitis with either open flap debridement with implantoplasty or open flap debridement alone.
1 surgery visit
Duration - 24 months
Participants are monitored for healing and treatment outcomes after surgery.
Regular follow-up visits over 24 months
Trial Site Locations
Total: 2 locations
1
Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo
Oslo, Oslo, Norway, 0455
Actively Recruiting
2
Institute of Clinical Dentistry, University of Oslo, Norway
Oslo, Norway
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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