Study Comparing Periacetabular Osteotomy Surgery With and Without Hip Arthroscopy for Hip Dysplasia in Patients Aged 16 to 50
Led by Ottawa Hospital Research Institute · Updated on 2025-12-30
204
Participants Needed
7
Research Sites
21 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying hip dysplasia, a condition where the hip socket develops abnormally causing joint stress and early arthritis. This trial aims to find out if adding a hip arthroscopy procedure to a periacetabular osteotomy PAO surgery improves patient outcomes compared to PAO alone. Patients with symptomatic acetabular dysplasia will be randomly assigned to receive either treatment and followed for two years to assess differences in symptoms and recovery.
The study compares two groups one receiving only the PAO surgery, which repositions the hip socket to reduce joint stress, and another receiving PAO combined with hip arthroscopy, a minimally invasive procedure to address additional joint abnormalities like labral tears. Both treatments are surgical, and the decision to operate is made by the patient and surgeon. The study will evaluate the added benefit of performing hip arthroscopy alongside PAO.
Participants will undergo assessments before surgery and at 6, 12, and 24 months after surgery, including questionnaires measuring hip function and quality of life. Researchers will also track operative time, hospital stay length, adverse events, and cost-effectiveness. Follow-up visits will monitor recovery over two years, focusing on patient-reported outcomes and safety.
CONDITIONS
Brief Title
Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology
Research Team
G
Geoffrey Wilkin, MD
C
Cheryl Kreviazuk
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This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
Factors
PAO with hip arthroscopy
PAO without hip arthroscopy
What it is
The investigational arm involves performing a Bernese periacetabular osteotomy (PAO) with additional central compartment hip arthroscopy for patients with acetabular dysplasia or hip instability.
The comparator arm involves performing PAO alone without hip arthroscopy for the same patient group.
Role in the trial
Serves as the investigational surgical technique to evaluate whether hip arthroscopy improves outcomes when combined with PAO.
Acts as the active comparator to measure outcomes of PAO performed without the addition of hip arthroscopy.
Primary use
Addresses hip instability and acetabular dysplasia by combining joint-preserving osteotomy with targeted arthroscopic correction of central compartment pathology.
Treats hip instability and acetabular dysplasia by realigning the acetabulum through PAO without additional joint procedures.
How it is given or performed
Performed as a single combined surgical event: hip arthroscopy for central compartment pathology followed immediately by PAO.
Performed as PAO alone without arthroscopy, following standard surgical technique for acetabular realignment.
Important limitations
This combined approach may increase operative time, complexity, and potential risk without clear evidence of improved patient-reported outcomes compared to PAO alone. Limitations include evolving indications for hip arthroscopy in dysplasia and lack of long-term outcome data.
PAO alone does not address central compartment pathology directly, which may leave some intra-articular damage uncorrected. Limitations include possible missed intra-articular pathology and similar lack of long-term comparative data.
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
Who Can Participate
Age: 16Years - 50Years
All Genders
Eligibility Criteria
You may qualify if you...
Skeletally mature patient undergoing Bernese periacetabular osteotomy for symptomatic acetabular dysplasia or hip instability
Pre-operative MRI at 3T and/or gadolinium MR arthrogram
Age between 16 and 50 years old
Patient capable of giving informed consent
You will not qualify if you...
Prior hip or pelvis surgery on the surgical side
Prior hip arthroplasty surgery on either side
Radiographic evidence of arthritis (Tönnis grade =2)
Known connective tissue disorders (e.g., Ehlers-Danlos Syndrome)
Known neuromuscular disorders (e.g., Cerebral Palsy, Spina bifida)
Known skeletal dysplasia (e.g., Achondroplasia, Multiple Epiphyseal Dysplasia)
Cognitive impairment preventing accurate completion of patient-reported outcome questionnaires
Patient unable or unwilling to complete all required follow-up visits
Concurrent proximal femoral osteotomy and/or surgical hip dislocation surgery
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Surgery and Immediate Post-operative Care
Duration - Up to 1 month
Participants undergo a periacetabular osteotomy (PAO) surgery, with some receiving an additional hip arthroscopy. This stage includes the surgery and the immediate recovery period in the hospital.
Hospital stay and follow-up visits during the first month post-surgery
Post-operative Follow-up
Duration - 24 months
Participants have scheduled visits to monitor recovery, assess symptoms, and evaluate outcomes after surgery.
Visits before surgery, and at 2-4 weeks, 3 months, 6 months, 12 months, and 24 months after surgery
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
The Otto Aufranc Award: Does Hip Arthroscopy at the Time of Periacetabular Osteotomy Improve the Clinical Outcome for the Treatment of Hip Dysplasia? A Multicenter Randomized Clinical Trial.
Paul E Beaulé, Jeroen C F Verhaegen, John C Clohisy...
Periacetabular osteotomy with or without arthroscopic management in patients with hip dysplasia: study protocol for a multicenter randomized controlled trial.
Geoffrey P Wilkin, Stéphane Poitras, John Clohisy...