Actively Recruiting
Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty
Led by Centre Hospitalier Universitaire Vaudois · Updated on 2024-08-22
80
Participants Needed
1
Research Sites
137 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this clinical trial is to compare the analgesic effect of pericapsular nerve block (PENG) with intrathecal morphine in patients scheduled for total hip replacement surgery. The main question to be answered is whether the PENG block is equivalent to intrathecal morphine in reducing postoperative pain. Participants will be randomised into two groups. Patients assigned to the PENG group will receive spinal anaesthesia with local anaesthetic (isobaric bupivacaine) alone and a PENG block. Patients assigned to the intrathecal morphine (ITM) group will receive spinal anaesthesia with a mixture of local anaesthetic (isobaric bupivacaine) and morphine (100 mcg) and a sham PENG block to ensure patient blinding.
CONDITIONS
Official Title
Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female patients
- ASA (American Society of Anaesthesiologists) physical status I to III
- 18 years of age or older
- Patients scheduled for elective primary hip arthroplasty
- Able to give written informed consent independently
You will not qualify if you...
- Refusal or inability to give consent
- Allergy to ropivacaine, paracetamol, ibuprofen, ketorolac, morphine, ondansetron, or dexamethasone
- Bleeding disorders
- Neurological deficit on the side to be operated on
- Current use of opioid medications before surgery
- Kidney failure with GFR less than 30 ml/min
- Liver failure
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital of Lausanne
Lausanne, Canton of Vaud, Switzerland, 1011
Actively Recruiting
Research Team
E
Eric Albrecht, Prof
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here