Comparing Pericapsular Nerve Block and Intrathecal Morphine for Pain Relief After Primary Hip Replacement Surgery

What this Trial Is About

Researchers are evaluating the pain relief effect of a pericapsular nerve block PENG compared to intrathecal morphine in patients undergoing total hip replacement surgery. This double-blind, non-inferiority study aims to determine if the PENG block provides similar postoperative pain control as intrathecal morphine by comparing morphine consumption, pain scores, side effects, and functional outcomes. Eighty patients will be randomly divided into two groups. One group will receive spinal anesthesia with local anesthetic and a PENG block, while the other will receive spinal anesthesia with local anesthetic plus intrathecal morphine and a sham PENG block to maintain blinding. During surgery, additional medications like dexamethasone, acetaminophen, ketorolac, and magnesium will support postoperative pain control. After surgery, pain will be managed with morphine as needed, along with paracetamol and ibuprofen. Participants will be closely monitored with post-operative visits at 2 hours, 1 day, and 2 days after surgery to collect data on pain, morphine use, side effects, and functional tests like walking and muscle strength. Pain management and any side effects such as nausea, itching, or urinary retention will be recorded. The main outcome is the total morphine used within the first 24 hours after surgery, with additional measures taken up to 2 days postoperatively.

Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty