Actively Recruiting
Comparing Two Regional Anesthesia Methods for Pain Relief After Anterior Approach Total Hip Replacement Surgery
Led by Ospedale Edoardo Bassini · Updated on 2026-03-25
102
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are comparing two regional anesthesia methods to manage pain after elective total hip arthroplasty THA performed via the anterior approach. This randomized controlled trial evaluates the use of a Pericapsular Nerve Group PENG block combined either with a Lateral Femoral Cutaneous Nerve LFCN block or with wound infiltration WI to find which method better controls postoperative pain. The study focuses on pain intensity at rest six hours after surgery and also looks at other factors like opioid use and mobility. Participants will be randomly assigned to one of two groups. One group receives a PENG block with an LFCN block under ultrasound guidance, using 20 ml and 10 ml of 0.5% ropivacaine respectively, following neuraxial anesthesia. The other group receives a PENG block with 20 ml of 0.5% ropivacaine and a wound infiltration of 10 ml 0.5% ropivacaine after surgery. Both procedures are standard clinical practices with minimal additional risk. During the study, participants will be assessed for pain at rest and during movement at 6, 24, and 48 hours after regional anesthesia. Researchers will also measure opioid consumption, time to first rescue pain medication, muscle strength, hip flexion, length of hospital stay, and any complications. Safety is closely monitored throughout. Participation involves regular evaluations up to 48 hours post-surgery and observation of hospital stay length, with study activities concluding by November 2026.
CONDITIONS
Brief Title
Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial
Research Team
M
Matteo Coccolo, MD
A
Angelo Pezzi, MD
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here