Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05830630

Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery

Led by Tanta University · Updated on 2025-07-09

72

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This prospective randomized controlled study will be conducted to evaluate the analgesic effect of continuous perineural infusion of methylene blue with bupivacaine on acute postoperative pain and to evaluate its preventive role against chronic phantom pain in patients undergoing lower limb amputation surgery

CONDITIONS

Official Title

Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of both genders
  • Suffering from vascular insufficiency of one or both lower limbs
  • Scheduled for above or below knee amputation under general anesthesia
Not Eligible

You will not qualify if you...

  • History of allergy to local anesthetics
  • Allergy to methylene blue
  • Use of anticoagulants or presence of coagulopathy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tanta University

Tanta, Gharbia Governorate, Egypt, 31527

Actively Recruiting

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Research Team

O

Osama M Rehab, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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