Study of Gum Disease and Related Genetic, Inflammatory, and Microbial Factors in Adults with Obesity Receiving Bariatric Care

What this Trial Is About

Researchers are investigating the prevalence and severity of Periodontal Disease PD in adults with obesity who are receiving bariatric care. The study also aims to explore inflammatory biomarkers linked to PD in saliva, examine the association of FTO gene polymorphisms with PD prevalence, and analyze the subgingival microbial flora in this population. This is a cross-sectional observational study conducted at a bariatric clinic. Participants will undergo routine care including medical examination with recording of various parameters such as age, gender, smoking status, body composition, ethnicity, and body mass index. Blood samples will be taken for genetic analysis if DNA samples are not already available. All participants will receive a basic periodontal examination, and if signs of destructive periodontitis are detected, more detailed periodontal assessments and microbial sampling will be performed. During the single study visit, participants will have periodontal evaluations, saliva and subgingival plaque samples collected, and possibly blood samples taken. These assessments will take up to two hours from consent. Researchers will measure the prevalence of PD, inflammatory biomarkers in saliva, genetic polymorphisms, and microbial flora. There is no additional follow-up, and the study duration for each participant is limited to this single visit.

Periodontal Assessment of a Bariatric Care Population