Actively Recruiting

Age: 18Years +
All Genders
NCT07384221

Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients

Led by Saglik Bilimleri Universitesi · Updated on 2026-02-03

20

Participants Needed

1

Research Sites

16 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to evaluate the relationship between the severity of Pemphigus Vulgaris (a chronic autoimmune skin disease) and periodontal (gum) health. Researchers will assess disease activity using the Oral Disease Severity Score (ODSS) for mouth lesions and measure serum Desmoglein 1 and 3 levels through blood tests. These findings will be compared with clinical gum measurements, such as pocket depth and attachment levels. The study intends to determine how the clinical and biochemical severity of Pemphigus Vulgaris impacts periodontal tissues and overall oral health.

CONDITIONS

Official Title

Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years and older
  • Clinically and histopathologically confirmed diagnosis of Pemphigus Vulgaris
  • Presence of at least 10 natural teeth
  • Willingness to participate and signed informed consent
Not Eligible

You will not qualify if you...

  • Pregnancy or lactation
  • Use of systemic antibiotics or anti-inflammatory drugs within the last 3 months
  • Periodontal treatment received within the last 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Health Sciences, Gulhane Faculty of Dentistry, Department of Periodontology

Ankara, Turkey (Türkiye), 06010

Actively Recruiting

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Research Team

B

Bilkan KARA, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients | DecenTrialz