Measuring Energy Use and Fitness Before and After Major Liver Surgery to Improve Recovery

What this Trial Is About

Researchers are studying patients undergoing major elective liver surgery to better understand how their energy use changes before and after the operation. This study focuses on how the bodys energy needs during recovery relate to a patients aerobic fitness before surgery. It aims to improve personalized exercise programs that might help unfit patients recover better and reduce complications after surgery. The study observes patients without changing their treatment. It measures energy use with advanced methods like doubly labelled water and indirect calorimetry one week before and after surgery, and during hospital stays. Aerobic fitness is tested with exercise tests before surgery and at discharge. Physical activity is tracked using small wearable devices. Questionnaires about anxiety and depression are also used to understand their impact on activity and recovery. Participants will be involved in tests and measurements before and after surgery, including urine collection, exercise testing, and wearing activity monitors. Researchers assess changes in energy use, fitness, physical activity, and postoperative complications. The study lasts about 18 months and includes detailed monitoring to gather data that may help improve care for future patients undergoing major liver surgery.

Perioperative Energy Expenditure in Major Liver Resection