Actively Recruiting
Perioperative Opioid-sparing Effect of Retrosuperior Costotransverse Ligament Block Versus Erector Spinae Block in Laparoscopic Cholecystectomy: A Randomized Clinical Trial.
Led by Zagazig University · Updated on 2025-12-12
80
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the analgesic effects of two nerve block techniques—the retro superior costotransverse ligament space block and the erector spinae plane block—in adults undergoing elective laparoscopic cholecystectomy. The study aims to compare their ability to reduce opioid use during and after surgery, maintain stable blood pressure and heart rate, and achieve high satisfaction for both patients and surgeons. Participants will be randomly assigned to receive either the retrosuperior costotransverse ligament block or the erector spinae block during surgery. The study monitors the time taken to perform each block, intraoperative fentanyl use, and hemodynamic parameters throughout the surgery. Both groups will be observed for postoperative pain scores, analgesic consumption, patient and surgeon satisfaction, and any complications related to the blocks. During the study, participants will be closely monitored for 24 hours after surgery to assess pain intensity at multiple time points and the time until the first request for additional pain relief. Vital signs will be recorded frequently during surgery. Patient satisfaction and any block-related complications will also be evaluated. The total duration of involvement covers the surgery and up to 24 hours after for outcome assessments.
CONDITIONS
Brief Title
Perioperative Opioid-sparing Effect of Retrosuperior Costotransverse Ligament Block Versus Erector Spinae Block in Laparoscopic Cholecystectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient acceptance
- Age between 21 and 64 years old
- Both male and female sexes
- Physical status ASA I or II
- Body mass index between 18.5 and 30 kg/m2
- Scheduled for elective laparoscopic cholecystectomy
- Surgery duration not more than 2 hours
You will not qualify if you...
- Known allergy to lidocaine or bupivacaine
- Respiratory insufficiency
- Coagulation disorders or use of drugs affecting surgical hemostasis
- Pre-existing neurological deficits
- Uncooperative or altered mental status
- Advanced cardiovascular or respiratory diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 2 hours (duration of surgery)
Participants receive either retrosuperior costotransverse ligament block or erector spinae block during laparoscopic cholecystectomy surgery.
1 visit (day of surgery, in-person)
Duration - 24 hours postoperative
Participants are monitored for pain intensity, analgesic use, patient satisfaction, and complications after surgery.
Multiple assessments at 30 minutes, 2, 4, 6, 8, 12, 18, and 24 hours after surgery (in-person)
Trial Site Locations
Total: 1 location
1
Faculty of human medicine, Zagazig university, Zagazig
Zagazig, Egypt
Actively Recruiting
Research Team
D
Dina Salem, MD
M
Marwa Medhat, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here