Actively Recruiting
The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
Led by King Abdullah International Medical Research Center · Updated on 2025-07-28
80
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this clinical trial is to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative blood loss, thromboembolic complications, and hospitalization duration in patients undergoing knee joint arthroplasty. Also aim to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative thromboembolic complications, and hospitalization duration
CONDITIONS
Official Title
The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing knee joint arthroplasty
- Saudi and Non-Saudi patients
- Patients who have a complete medical record
You will not qualify if you...
- End stage renal disease
- Liver cirrhosis
- Coagulopathy
- Pre-operative hemoglobin less than 10.5
- History of cerebrovascular accident or myocardial infarction in past 12 months
- History of heart failure
- History of arrhythmia
- History of pheochromocytoma, thyrotoxicosis, or glaucoma
- Pregnancy or breastfeeding
- History of deep venous thrombosis or pulmonary embolism
- Allergy to epinephrine or tranexamic acid
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
King Abdulaziz Medical City, Ministry of National Guard - Health Affairs
Riyadh, Riyadh Region, Saudi Arabia
Actively Recruiting
Research Team
D
Dr. Turki Althunayan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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