The validity and practicality of sun-reactive skin types I through VI.
T B Fitzpatrick
https://pubmed.ncbi.nlm.nih.gov/3377516Actively Recruiting
Age: 20Years - 35Years
All Genders
Healthy Volunteers
ID06732609
Clinical Evaluation and Characterization of Normal Perioral Tissue Using Advanced Videodermoscopy A Pilot Study on Dental Students
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2024-12-13
80
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting an observational pilot study to carefully examine the normal skin and mucosal structures around the mouth in healthy young adults aged 20 to 35 years. The study aims to document details like pores, fine lines, texture, pigmentation, vascular patterns, and skin irregularities in specific areas such as the anterior chin, vermilion border, and vermilion zone. This detailed evaluation introduces new imaging findings to better understand the complex features of healthy perioral tissue. The study uses advanced imaging tools, including the Horus 1000VMF system with two dermatoscopic probes at 30x and 150x magnification and a Fluorescence Advanced Videodermatoscopy (FAV) probe at 500x magnification. These devices capture detailed images under different light modes to observe surface and deeper skin layers. Before imaging, the skin is cleaned and treated with glycerol for clarity. Images from three key mouth areas are taken, stored, and independently reviewed by trained investigators. Participants will have their perioral region imaged and assessed over 8 weeks, with the research team analyzing characteristics like mucosal health, surface texture, and skin features using specialized classifications for skin type and phototype. Data on age, sex, and skin type are also collected to provide a comprehensive picture. The study carefully monitors participants to ensure consistent, unbiased image analysis, supporting future research on perioral skin.
CONDITIONS
Brief Title
Perioral Tissue Evaluation With Advanced Videodermoscopy (FAV)
Who Can Participate
Age: 20Years - 35Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Participants must be between 20 and 35 years old
- Must be in good general health with no known systemic diseases (ASA I)
- Must have clinically healthy skin in the target area with no history of eczema, psoriasis, or dermatitis
- Must provide written informed consent to participate
- Must be non-smokers or have quit smoking for at least 12 months
- Must not have had recent skin treatments (laser, chemical peels, topical meds) in the area within the last 3 months
You will not qualify if you...
- History of skin diseases like acne, psoriasis, eczema, or other interfering skin conditions
- Presence of chronic systemic illnesses such as diabetes or autoimmune diseases
- Current use of medications that could alter skin (corticosteroids, retinoids, immunosuppressants)
- Known allergies to topical products used during examination
- Pregnant or breastfeeding individuals
- Recent dermatological procedures in the area within the last 3 months
- Recent excessive sun exposure or sunburns in the target area within the last 2 months
- Unwillingness or inability to follow study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Up to 8 weeks
Participants undergo detailed imaging and clinical evaluation of the perioral tissue using advanced videodermoscopy and fluorescence techniques.
1 to 3 visits for image acquisition and evaluation
Long-term Monitoring
Duration - Up to 8 weeks
Participants' perioral tissue images and characteristics are monitored and analyzed over time to assess variability and stability of skin features.
Follow-up assessments as scheduled within 8 weeks
Trial Site Locations
Total: 1 location
1
UOC Clinica Odontoiatrica, Fondazione Policlinico Agostino Gemelli IRCCS
Roma, Italy, 00168
Actively Recruiting
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Research Team
A
Andrea Camodeca, DMD, MSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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On the use of a pilot sample for sample size determination.
R H Browne
https://pubmed.ncbi.nlm.nih.gov/8532986Skin typing: Fitzpatrick grading and others.
Vishal Gupta, Vinod Kumar Sharma
https://pubmed.ncbi.nlm.nih.gov/31896400Diagnostics Using Non-Invasive Technologies in Dermatological Oncology.
Simone Soglia, Javiera Pérez-Anker, Nelson Lobos Guede...
https://pubmed.ncbi.nlm.nih.gov/36497368Fluorescence-advanced videodermatoscopy: a new method for in vivo skin evaluation.
M Sanlorenzo, I Vujic, V De Giorgi...
https://pubmed.ncbi.nlm.nih.gov/28421598Dermoscopy of pigmented skin lesions--a valuable tool for early diagnosis of melanoma.
G Argenziano, H P Soyer
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https://pubmed.ncbi.nlm.nih.gov/33302498