Diagnostics Using Non-Invasive Technologies in Dermatological Oncology.
Simone Soglia, Javiera Pérez-Anker, Nelson Lobos Guede...
https://pubmed.ncbi.nlm.nih.gov/36497368/Actively Recruiting
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2024-12-13
80
Participants Needed
1
Research Sites
8 weeks
Total Duration
Researchers are conducting an observational pilot study to carefully examine the normal skin and mucosal structures around the mouth in healthy young adults aged 20 to 35 years. The study aims to document details like pores, fine lines, texture, pigmentation, vascular patterns, and skin irregularities in specific areas such as the anterior chin, vermilion border, and vermilion zone. This detailed evaluation introduces new imaging findings to better understand the complex features of healthy perioral tissue. The study uses advanced imaging tools, including the Horus 1000VMF system with two dermatoscopic probes at 30x and 150x magnification and a Fluorescence Advanced Videodermatoscopy FAV probe at 500x magnification. These devices capture detailed images under different light modes to observe surface and deeper skin layers. Before imaging, the skin is cleaned and treated with glycerol for clarity. Images from three key mouth areas are taken, stored, and independently reviewed by trained investigators. Participants will have their perioral region imaged and assessed over 8 weeks, with the research team analyzing characteristics like mucosal health, surface texture, and skin features using specialized classifications for skin type and phototype. Data on age, sex, and skin type are also collected to provide a comprehensive picture. The study carefully monitors participants to ensure consistent, unbiased image analysis, supporting future research on perioral skin.
CONDITIONS
Perioral Tissue Evaluation With Advanced Videodermoscopy (FAV)
A
Andrea Camodeca, DMD, MSc
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 8 weeks
Participants undergo detailed imaging and clinical evaluation of the perioral tissue using advanced videodermoscopy and fluorescence techniques.
1 to 3 visits for image acquisition and evaluation
Duration - Up to 8 weeks
Participants' perioral tissue images and characteristics are monitored and analyzed over time to assess variability and stability of skin features.
Follow-up assessments as scheduled within 8 weeks
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Have more questions? Get in touch with our team for quick support
Simone Soglia, Javiera Pérez-Anker, Nelson Lobos Guede...
https://pubmed.ncbi.nlm.nih.gov/36497368/Salvador González, Zeina Tannous
https://pubmed.ncbi.nlm.nih.gov/12451371/Vishal Gupta, Vinod Kumar Sharma
https://pubmed.ncbi.nlm.nih.gov/31896400/Silvio Abati, Chiara Bramati, Stefano Bondi...
https://pubmed.ncbi.nlm.nih.gov/33302498/T B Fitzpatrick
https://pubmed.ncbi.nlm.nih.gov/3377516/R H Browne
https://pubmed.ncbi.nlm.nih.gov/8532986/M Sanlorenzo, I Vujic, V De Giorgi...
https://pubmed.ncbi.nlm.nih.gov/28421598/G Argenziano, H P Soyer
https://pubmed.ncbi.nlm.nih.gov/11905739/Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead Sponsor