Actively Recruiting

Age: 20Years - 35Years
All Genders
Healthy Volunteers
NCT06732609

Perioral Tissue Evaluation With Advanced Videodermoscopy (FAV)

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2024-12-13

80

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary aim of this study is to characterize and systematically document the key dermato-mucosal structures of the perioral region in physiological conditions. Relative to the anterior chin area (ACA), the authors have tried to identify and describe pores, fine lines or wrinkles, texture patterns, superficial desquamation, hair follicles, sebaceous glands, fine ridges, grooves, sebaceous ducts, and skin irregularities. The observed features of the vermilion border (VB) and vermilion zone (VZ) include variations in color, texture, and surface characteristics, alongside the presence of fine lines and grooves. Vascular patterns and capillary visibility were observed, with pigmentation patterns providing additional insights into structural uniformity and non-uniform areas. Shiny surfaces, pore visibility, and regional differences in sebaceous activity and texture were also highlighted, reflecting the complex variability across the vermilion zone. Additionally, novel dermatoscopic and FAV findings not previously described in the literature were introduced into the analysis based on the personal observations of the investigators. This allowed for a comprehensive evaluation of the skin characteristics, providing a detailed analysis for each anatomical zone studied.

CONDITIONS

Official Title

Perioral Tissue Evaluation With Advanced Videodermoscopy (FAV)

Who Can Participate

Age: 20Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be between 20 and 35 years old
  • Participants must be in good general health with no known systemic diseases (ASA I)
  • Participants must have clinically healthy skin in the target area with no history of dermatological conditions such as eczema, psoriasis, or dermatitis
  • Participants must provide written informed consent
  • Participants should be non-smokers or have quit smoking for at least 12 months
  • Participants must not have received treatments affecting the skin in the area of interest within the last 3 months (e.g., laser treatments, chemical peels, topical medications)
Not Eligible

You will not qualify if you...

  • History of skin diseases such as acne, psoriasis, eczema, or other conditions interfering with assessment
  • Presence of chronic systemic illnesses like diabetes or autoimmune diseases affecting skin health
  • Current use of medications or treatments altering skin characteristics (e.g., corticosteroids, retinoids, immunosuppressants)
  • Known allergies to topical products used during the examination
  • Pregnancy or breastfeeding
  • Recent dermatological procedures within the last 3 months in the area of evaluation
  • Recent excessive sun exposure or sunburns in the target area within the last 2 months
  • Unwillingness or inability to comply with study procedures

AI-Screening

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Trial Site Locations

Total: 1 location

1

UOC Clinica Odontoiatrica, Fondazione Policlinico Agostino Gemelli IRCCS

Roma, Italy, 00168

Actively Recruiting

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Research Team

A

Andrea Camodeca, DMD, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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