Study of Peripheral Nerve Activation Sensitivity to Electric and Electromagnetic Stimulation in the Upper Arm for Healthy Adults

What this Trial Is About

Researchers are studying nerve excitation sensitivity in healthy volunteers to understand how different methods of peripheral nerve stimulation affect nerve activation. This study evaluates electric, electromagnetic, and temporal interference stimulations in the upper arm, focusing on the relationship between nerve activation and coil placement as well as how various coil types influence maximal nerve response. Participants will receive momentary, non-therapeutic electric and electromagnetic stimulations using different coil designs and electrodes. These stimulations are applied to assess peripheral nerve sensitivity during a single study day. The study measures maximum nerve activation response with different coils and evaluates the spatial range of nerve activation and amplitude ratios associated with nerve stimulation. During the study, volunteers will undergo various stimulations of the upper arm nerves. Researchers will monitor nerve activation using different coils and electrodes, and collect data on responses to these stimulations. The primary outcome is the maximal activation response to electromagnetic stimulation, with secondary outcomes including spatial activation ranges and amplitude ratios. Participants need to be healthy and able to follow study procedures, with total involvement lasting one day.

Peripheral Nerve Activation Sensitivity