Actively Recruiting
Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy
Led by University of Aarhus · Updated on 2021-01-07
16
Participants Needed
1
Research Sites
329 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the present study is to evaluate the role of peripheral afferent input for spontaneous pain in painful diabetic polyneuropathy
CONDITIONS
Official Title
Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older.
- Probably diabetic neuropathy confirmed using the Toronto criteria in a "conservative manner", i.e. three out of three symptoms/signs of neuropathy must be present (sensory neuropathy symptoms, distal reduced sensibility, reduced ankle reflexes) 7.
- Definite or probable neuropathic pain for minimum the last 6 months
- Mean pain intensity at > 4 NRS the last week17.
Since we expect a large effect of the block it is not necessary to discontinue pain medication.
You will not qualify if you...
- Other causes of pain in the same area or other pain that cannot be distinguished from the neuropathic pain.
- Unable to understand and speak Danish.
- Non-cooperative.
- Warfarin or other medication that contraindicate regional anesthesia.
- Infection in the injection area.
- Allergy to lidocaine.
- Pregnancy or lactating (fertile women must to show negative pregnancy test or use anticonception).
- Severe psychiatric disease e.g. severe depression during the last 6 months.
- Alcohol or drug abuse.
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Trial Site Locations
Total: 1 location
1
Danish Pain Research Center, Aarhus University, Aarhus University Hospital
Aarhus N, Jutland, Denmark, 8200
Actively Recruiting
Research Team
E
Ellen L Schaldemose, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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