Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06004882

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

Led by M.D. Anderson Cancer Center · Updated on 2026-03-03

45

Participants Needed

1

Research Sites

181 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain: * A standard steroid injection * Peripheral nerve stimulation (PNS) therapy in combination with a standard steroid injection * PNS therapy in combination with a placebo injection Steroid injections are given directly into the knee joints and are considered to be the standard therapy for chronic knee pain. In this study, the injection will be made of the steroid drugs triamcinolone and bupivacaine.

CONDITIONS

Official Title

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with chronic knee pain with a baseline pain score of 4 or higher
  • Patients between 18 and 85 years old
  • Patients who have signed informed consent
Not Eligible

You will not qualify if you...

  • Patients with cognitive dysfunction or without capacity to consent
  • Patients with a history of drug or alcohol abuse within the past 6 months
  • Patients with open skin lesions or undergoing antibiotic treatment for local or systemic infection
  • Patients allergic to local anesthesia, steroids, or adhesives
  • Patients using opioids for reasons other than knee pain

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

S

Saba Javed, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

3

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