Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06422845

Peripheral Scoring Drug-coated Balloon in the Treatment of Hemodialysis Arteriovenous Fistula Stenosis

Led by DK Medical Technology (Suzhou) Co., Ltd. · Updated on 2025-01-09

328

Participants Needed

33

Research Sites

143 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, multi-center, single-arm target value clinical study to study the safety and effectiveness of Peripheral Scoring Drug-coated Balloon dilatation catheters in the treatment of hemodialysis arteriovenous fistula stenosis.

CONDITIONS

Official Title

Peripheral Scoring Drug-coated Balloon in the Treatment of Hemodialysis Arteriovenous Fistula Stenosis

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 80 years old
  • Mature arteriovenous fistula or graft with at least one successful hemodialysis session
  • Target lesion located at the return vein and venous side anastomosis of AVF/AVG
  • Hemodynamically significant stenosis of 50% or more confirmed by ultrasound or contrast imaging with related clinical symptoms
  • Target lesion may be primary or restenotic and include one or more tandem lesions with total length up to 60 mm
  • Reference blood vessel diameter between 4.0 and 8.0 mm; total lesion length up to 60 mm
  • Voluntary signed informed consent
Not Eligible

You will not qualify if you...

  • Women of childbearing age without a negative pregnancy test or who are breastfeeding
  • Major surgery within 30 days before enrollment
  • Calcified lesions unlikely to expand with balloons
  • Thrombosis at the stenosis site
  • Lesions located at blood supply artery or arterial anastomosis
  • Known allergy or intolerance to contrast media or paclitaxel
  • Life expectancy less than 2 years
  • Systemic lupus erythematosus or ANCA-associated small vessel vasculitis
  • History of kidney transplantation or planned transplant or switch to peritoneal dialysis
  • Vascular access or systemic active infection
  • Participation in unfinished clinical trials of other drugs or devices
  • Other medical conditions deemed unsuitable by the investigator

AI-Screening

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Trial Site Locations

Total: 33 locations

1

The Second Hospital of Anhui Medical University

Hefei, Anhui, China

Not Yet Recruiting

2

Beijing Haidian Hospital

Beijing, Beijing Municipality, China

Actively Recruiting

3

The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Not Yet Recruiting

4

Guangzhou First People's Hospital

Guanzhou, Guangdong, China

Not Yet Recruiting

5

Huizhou Central People's Hospital

Huizhou, Guangdong, China

Not Yet Recruiting

6

Peking University Shenzhen Hospital

Shenzhen, Guangdong, China

Not Yet Recruiting

7

The Eighth Affiliated Hospital, Sun Yat-sen University

Shenzhen, Guangdong, China

Not Yet Recruiting

8

Liuzhou Traditional Chinese Medical Hospital

Liuzhou, Guangxi, China

Not Yet Recruiting

9

Foresea Life Insurance Guangxi Hospital

Nanning, Guangxi, China

Not Yet Recruiting

10

The Affiliated Cancer Hospital of Guizhou Medical University

Guiyang, Guizhou, China

Not Yet Recruiting

11

Henan Provincial People's Hospital

Zhengzhou, Henan, China

Not Yet Recruiting

12

Tongji Hospital Affiliated To Tongji Medical College HUST

Wuhan, Hubei, China

Not Yet Recruiting

13

Changsha Jieao Kidney Disease Hospital

Changsha, Hunan, China

Not Yet Recruiting

14

Hunan Provincial People's Hospital

Changsha, Hunan, China

Not Yet Recruiting

15

The Second Xiangya Hospital of Central South University

Changsha, Hunan, China

Not Yet Recruiting

16

The First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China

Not Yet Recruiting

17

The Affiliated Hospital To Changchun University of Chinese Medicine

Changchun, Jilin, China

Not Yet Recruiting

18

The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, China

Not Yet Recruiting

19

Qilu Hospital of Shandong University Dezhou Hospital

Dezhou, Shandong, China

Not Yet Recruiting

20

Central Hospital Affiliated To Shandong First Medical University

Jinan, Shandong, China

Not Yet Recruiting

21

The First Affiliated Hospital of Shandong First Medical University

Jinan, Shandong, China

Not Yet Recruiting

22

Qingdao Municipal Hospital

Qingdao, Shandong, China

Not Yet Recruiting

23

People's Hospital of Rizhao

Rizhao, Shandong, China

Not Yet Recruiting

24

Shanxi Bethune Hospital

Taiyuan, Shanxi, China

Not Yet Recruiting

25

Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital

Chengdu, Sichuan, China

Not Yet Recruiting

26

West China Hospital Sichuan University

Chengdu, Sichuan, China

Not Yet Recruiting

27

Mianyang Central Hospital

Mianyang, Sichuan, China

Not Yet Recruiting

28

Affiliated Hospital of North Sichuan Medical College

Nanchong, Sichuan, China

Not Yet Recruiting

29

Sir Run Run Shaw Hospital Zhejiang University School of medicine

Hangzhou, Zhejiang, China

Not Yet Recruiting

30

The First Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

Not Yet Recruiting

31

Jinhua Hospital of TCM

Jinhua, Zhejiang, China

Not Yet Recruiting

32

Taizhou Hospital of Zhejiang Province

Taizhou, Zhejiang, China

Not Yet Recruiting

33

The First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Ürümqi, China

Not Yet Recruiting

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Research Team

Y

Yuzhu Wang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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