Actively Recruiting

Phase 4
Age: 15Years - 17Years
All Genders
Healthy Volunteers
NCT07156084

Persistence of Immune Response Six Years After One Dose of 9vHPV Vaccine Among Male and Female Students

Led by Canadian Immunization Research Network · Updated on 2025-09-29

300

Participants Needed

1

Research Sites

18 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Since the 2019-2020 school year, the province of Quebec (Canada) has been administering one dose of nonavalent (9vHPV) vaccine to students of all genders in Grade 4 of elementary school through the school-based program. Little data on the immunogenicity (antibody production) and long-term efficacy of a single dose of the vaccine are available, particularly in boys. The primary objective of this study is to assess the persistence of HPV antibodies six years after the administration of a single dose of the 9vHPV vaccine to students aged 9 to 11 years in Grade 4 in 2019-2020. The study will be conducted at the CHU de Québec-Université Laval research center. Recruitment is conducted through school service centers in the Quebec City region. Youth who received only a single dose of the 9vHPV vaccine at the ages of 9-11 in 2019-2020 will be eligible to participate. Approximately 300 youth will take part in this study: 150 girls and 150 boys. Participants will have to answer few questions about their health to ensure their eligibility for the study. For eligible participants consenting to participate a 10 ml (\<1 tablespoon) blood sample will be taken.

CONDITIONS

Official Title

Persistence of Immune Response Six Years After One Dose of 9vHPV Vaccine Among Male and Female Students

Who Can Participate

Age: 15Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Received a single dose of 9vHPV vaccine at ages 9 to 11 during the 2019-2020 school year
  • Have not received any other HPV vaccine doses
  • Able to provide consent to participate in the study
Not Eligible

You will not qualify if you...

  • Immunosuppressed at the time of recruitment or at vaccination

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre de recherche du CHU de Québec-Université Laval

Québec, Quebec, Canada, G1X4S9

Actively Recruiting

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Research Team

C

Chantal Sauvageau, MD

CONTACT

J

Jo-Ann Costa

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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Persistence of Immune Response Six Years After One Dose of 9vHPV Vaccine Among Male and Female Students | DecenTrialz