Actively Recruiting
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Led by Zimmer Biomet · Updated on 2026-01-20
760
Participants Needed
16
Research Sites
622 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
CONDITIONS
Official Title
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient is 18 years or older and skeletally mature
- Patient is willing and able to provide written informed consent
- Patient is willing and able to complete all scheduled follow-up evaluations
- Patient qualifies for cemented or cementless primary or revision total knee arthroplasty with the Persona Knee System and compatible Zimmer Biomet components according to product labeling
You will not qualify if you...
- Currently participating in another surgical intervention or pain management study
- Pregnant or a member of a protected vulnerable population (e.g., prisoner, mentally incompetent)
- Has a mental or neurological condition preventing post-operative care compliance
- Has any condition placing the patient at undue risk or interfering with the study
- Institutionalized, known drug abuser, alcoholic, or unable to understand study requirements
- Scheduled for simultaneous bilateral total knee arthroplasty
- Previous infection in the affected joint or other local/systemic infections
- Insufficient bone stock on femoral or tibial surfaces
- Neuropathic arthropathy
- Osteoporosis or neuromuscular disease compromising the affected limb
- Stable, painless arthrodesis in a functional position
- Severe instability due to absence of collateral ligament integrity
- Rheumatoid arthritis with skin ulcer or recurrent skin breakdown
- Valgus deformity over 5° with medial collateral ligament insufficiency and planned personalized alignment surgical technique
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 16 locations
1
Denver Hip & Knee, Inc.
Parker, Colorado, United States, 80138
Actively Recruiting
2
Foundation for Orthopaedic Research & Education
Tampa, Florida, United States, 33607
Actively Recruiting
3
Northside Hospital, Inc.
Atlanta, Georgia, United States, 30342
Active, Not Recruiting
4
U of L Health
Louisville, Kentucky, United States, 40202
Actively Recruiting
5
University of Michigan
Ann Arbor, Michigan, United States, 48109
Active, Not Recruiting
6
Mayo Clinic
Rochester, Minnesota, United States, 55902
Actively Recruiting
7
Mississippi Sports Medicine and Orthopaedic Center
Jackson, Mississippi, United States, 39202
Active, Not Recruiting
8
New Mexico Orthopaedic Associates
Albuquerque, New Mexico, United States, 87110
Actively Recruiting
9
Syracuse Orthopaedic Specialists
DeWitt, New York, United States, 13214
Actively Recruiting
10
NYU
New York, New York, United States, 11016
Actively Recruiting
11
St. Francis Hospital & Heart Center
Roslyn, New York, United States, 11576
Actively Recruiting
12
OrthoCarolina Research Institute, Inc.
Charlotte, North Carolina, United States, 28207
Actively Recruiting
13
Duke University
Morrisville, North Carolina, United States, 27560
Actively Recruiting
14
Cleveland Clinic
Cleveland, Ohio, United States, 44195
Actively Recruiting
15
UT Health at Houston
Houston, Texas, United States, 77030
Actively Recruiting
16
UVA Health Orthopedic Center
Charlottesville, Virginia, United States, 22903
Active, Not Recruiting
Research Team
E
Erik Kowalski, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
12
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