Actively Recruiting
Personalised HeartCare: Poligenic Risk Scores Disclosure for Cardiovascular Prevention
Led by Catholic University of the Sacred Heart · Updated on 2026-02-20
650
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate whether the disclosure of Polygenic Risk Scores (PRS) combined with personalized coaching on risk factors can lead to significant improvements in lifestyle behaviors among staff members at Fondazione Policlinico Universitario Agostino Gemelli IRCCS. The study includes staff members from Fondazione Policlinico Universitario Agostino Gemelli IRCCS, enrolled at the outpatient clinics of the Cardiology Department. Main Research Questions: 1. Does receiving PRS disclosure and personalized coaching lead to significant improvements in lifestyle behaviors compared to baseline measurements? 2. How do different levels of genetic predisposition to cardiovascular diseases (CVD) impact behavioral changes following intervention? This is a single arm, pre-post clinical trial. Participant will: * Undergo genetic testing to assess their Polygenic Risk Score for CVDs * receive personalized, in-person consultation with a medical cardiologis, together with and individualized recommendations for CVD prevention based on PRS results and traditional risk factors.
CONDITIONS
Official Title
Personalised HeartCare: Poligenic Risk Scores Disclosure for Cardiovascular Prevention
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Traditional cardiovascular risk assessed using SCORE 2 or SCORE 2-OP with low to moderate risk levels
- Blood tests performed within the past 6 months
- Age of 40 years or older
You will not qualify if you...
- Very high cardiovascular risk as measured by SCORE 2 or SCORE 2-OP
- Diagnosis of diabetes
- Familial hypercholesterolemia
- Previous cardiovascular events or established cardiovascular disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dipartimento Universitario di Scienze della Vita e Sanità Pubblica
Roma, Italia, Italy, 00168
Actively Recruiting
Research Team
S
Stefania Boccia
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here